The capacity for regeneration is broad in the animal kingdom. Planarians are flatworms that
can regenerate any missing body part and their regenerative powers have combined with …

Planarians are flatworms capable of whole-body regeneration, able to regrow any missing
body part after injury or amputation. The extraordinary regenerative capacity of planarians is …

Planarians have become an established model system to study regeneration and stem cells,
but the regulatory elements in the genome remain almost entirely undescribed. Here, by …

Adult planarians can regenerate the gut, eyes and even a functional brain. Proper identity
and patterning of the newly formed structures require signals that guide and commit their …

In developmental biology, the regulation of stem cell plasticity and differentiation remains an
open question. CBP (CREB-binding protein)/p300 is a conserved gene family that functions …

Lipid metabolism plays an instructive role in regulating stem cell state and differentiation.
However, the roles of lipid mobilization and utilization in stem cell-driven regeneration are …

Regeneration is the regrowth of damaged tissues or organs, a vital process in response to
damages from primitive organisms to higher mammals. Planarian possesses active whole …

Glia play multifaceted roles in nervous systems in response to injury. Depending on the
species, extent of injury and glial cell type in question, glia can help or hinder the …

Abstract Background The flatworm planarian, Schmidtea mediterranea, has a large
population of adult stem cells (ASCs) that replace any cell type during tissue turnover or …

Planarians, a type of flatworm, possess the remarkable ability of complete bodily
regeneration, enabling them to redevelop any absent anatomical component following injury …