Inflammation and oxidative stress in multiple sclerosis: consequences for therapy development
V Pegoretti, KA Swanson, JR Bethea… - Oxidative medicine …, 2020 - Wiley Online Library
CNS inflammation is a major driver of MS pathology. Differential immune responses,
including the adaptive and the innate immune system, are observed at various stages of MS …
including the adaptive and the innate immune system, are observed at various stages of MS …
Epidemiology, diagnosis and management of sexual dysfunction in multiple sclerosis
J Drulovic, D Kisic-Tepavcevic, T Pekmezovic - Acta Neurologica Belgica, 2020 - Springer
Multiple sclerosis (MS) is the most common chronic neurological disorder in young adults,
with numerous potential effects on neurologic function. Sexual dysfunction (SD) is a …
with numerous potential effects on neurologic function. Sexual dysfunction (SD) is a …
[HTML][HTML] Pain in people with multiple sclerosis: associations with modifiable lifestyle factors, fatigue, depression, anxiety, and mental health quality of life
Background People with multiple sclerosis (MS) often experience pain, which can interfere
with mobility, employment, and quality of life (QOL). Methods This cross-sectional study …
with mobility, employment, and quality of life (QOL). Methods This cross-sectional study …
Regulatory T cells and their derived cytokine, interleukin-35, reduce pain in experimental autoimmune encephalomyelitis
SS Duffy, BA Keating, CJ Perera, JG Lees… - Journal of …, 2019 - Soc Neuroscience
Sensory problems such as neuropathic pain are common and debilitating symptoms in
multiple sclerosis (MS), an autoimmune inflammatory disorder of the CNS. Regulatory T …
multiple sclerosis (MS), an autoimmune inflammatory disorder of the CNS. Regulatory T …
Endoplasmic reticulum stress in the dorsal root ganglia regulates large‐conductance potassium channels and contributes to pain in a model of multiple sclerosis
MS Yousuf, S Samtleben, SM Lamothe… - The FASEB …, 2020 - Wiley Online Library
Neuropathic pain is a common symptom of multiple sclerosis (MS) and current treatment
options are ineffective. In this study, we investigated whether endoplasmic reticulum (ER) …
options are ineffective. In this study, we investigated whether endoplasmic reticulum (ER) …
Fingolimod reduces neuropathic pain behaviors in a mouse model of multiple sclerosis by a sphingosine-1 phosphate receptor 1-dependent inhibition of central …
Multiple sclerosis (MS) is an autoimmune-inflammatory neurodegenerative disease that is
often accompanied by a debilitating neuropathic pain. Disease-modifying agents slow down …
often accompanied by a debilitating neuropathic pain. Disease-modifying agents slow down …
[HTML][HTML] Peripheral and central neuroinflammatory changes and pain behaviors in an animal model of multiple sclerosis
SS Duffy, CJ Perera, PGS Makker, JG Lees… - Frontiers in …, 2016 - frontiersin.org
Pain is a widespread and debilitating symptom of multiple sclerosis (MS), a chronic
inflammatory demyelinating disease of the central nervous system. Although central …
inflammatory demyelinating disease of the central nervous system. Although central …
Impact of multiple sclerosis on male sexual and reproductive health
H Geng, Q Ye, X Lin, S Simpson-Yap, Y Zhou… - Multiple Sclerosis and …, 2023 - Elsevier
Multiple sclerosis (MS) is a chronic inflammatory and autoimmune neurodegenerative
disease characterized by the destruction of myelin in the central nervous system, leading to …
disease characterized by the destruction of myelin in the central nervous system, leading to …
Central amygdala inflammation drives pain hypersensitivity and attenuates morphine analgesia in experimental autoimmune encephalomyelitis
Chronic pain is a highly prevalent symptom associated with the autoimmune disorder
multiple sclerosis (MS). The central nucleus of the amygdala plays a critical role in pain …
multiple sclerosis (MS). The central nucleus of the amygdala plays a critical role in pain …
Pharmacological and Non-pharmacological Approaches for the Management of Neuropathic Pain in Multiple Sclerosis
Multiple sclerosis is a chronic inflammatory disease that affects the central nervous system
and can cause various types of pain including ongoing extremity pain, Lhermitte's …
and can cause various types of pain including ongoing extremity pain, Lhermitte's …