Molecular mechanisms for enhanced DNA vaccine immunogenicity

L Li, N Petrovsky - Expert review of vaccines, 2016 - Taylor & Francis
In the two decades since their initial discovery, DNA vaccines technologies have come a
long way. Unfortunately, when applied to human subjects inadequate immunogenicity is still …

DNA vaccination for finfish aquaculture

C Collins, N Lorenzen, B Collet - Fish & shellfish immunology, 2019 - Elsevier
In fish, DNA vaccines have been shown to give very high protection in experimental facilities
against a number of viral diseases, particularly diseases caused by rhabdoviruses …

Targeted delivery of nanovaccine to dendritic cells via DC-binding peptides induces potent antiviral immunity in vivo

Y Lu, ZH Liu, YX Li, HL Xu, WH Fang… - International Journal of …, 2022 - Taylor & Francis
Background Dendritic cell (DC) targeted antigen delivery is a promising strategy to enhance
vaccine efficacy and delivery of therapeutics. Self-assembling peptide-based nanoparticles …

Targeting the central nervous system (CNS): a review of rabies virus-targeting strategies

M Oswald, S Geissler, A Goepferich - Molecular pharmaceutics, 2017 - ACS Publications
The transport of drugs across the blood–brain barrier is challenging. The use of peptide
sequences derived from viruses with a central nervous system (CNS) tropism is one elegant …

DNA vaccines for prostate cancer

CD Zahm, VT Colluru, DG McNeel - Pharmacology & therapeutics, 2017 - Elsevier
DNA vaccines offer many advantages over other anti-tumor vaccine approaches due to their
simplicity, ease of manufacturing, and safety. Results from several clinical trials in patients …

Dendritic cells/macrophages-targeting feature of Ebola glycoprotein and its potential as immunological facilitator for antiviral vaccine approach

TA Olukitibi, Z Ao, M Mahmoudi, GA Kobinger, X Yao - Microorganisms, 2019 - mdpi.com
In the prevention of epidemic and pandemic viral infection, the use of the antiviral vaccine
has been the most successful biotechnological and biomedical approach. In recent times …

Enhanced contraception of canine zona pellucida 3 DNA vaccine via targeting DEC-205 in mice

Y Wang, B Zhang, J Li, A Aipire, Y Li, F Zhang - Theriogenology, 2018 - Elsevier
Abstract Zona pellucida 3 (ZP3) is a potential antigen for the development of contraceptive
vaccines to control animal population. In this study, we designed a canine ZP3 (CZP3) DNA …

Enhanced delivery of Mycobacterium tuberculosis antigens to antigen presenting cells using RVG peptide

O Garnica, K Das, S Devasundaram… - Tuberculosis, 2019 - Elsevier
Among the various strategies to improve vaccines against infectious diseases, targeting of
antigens to dendritic cells (DCs), which are professional antigen presenting cells (APCs) …

Development and characterization of a novel DC-targeting universal influenza vaccine

T Olukitibi - 2024 - mspace.lib.umanitoba.ca
The highly contagious pandemic potential influenza virus causes around 650,000 annual
deaths despite available vaccines. Developing a universal influenza vaccine is crucial for …

Targeted-delivery of small interference rna against anthrax

M Zeng - 2016 - Google Patents
WO2016205331A1 - Targeted-delivery of small interference rna against anthrax - Google
Patents WO2016205331A1 - Targeted-delivery of small interference rna against anthrax …