Copper homeostasis and cuproptosis in tumor pathogenesis and therapeutic strategies
C Bian, Z Zheng, J Su, S Chang, H Yu, J Bao… - Frontiers in …, 2023 - frontiersin.org
Copper is an indispensable micronutrient for the development and replication of all
eukaryotes, and its redox properties are both harmful and beneficial to cells. An imbalance …
eukaryotes, and its redox properties are both harmful and beneficial to cells. An imbalance …
lncRNAs as prognostic markers and therapeutic targets in cuproptosis-mediated cancer
Long non-coding RNAs (lncRNAs) have emerged as crucial regulators in various cellular
processes, including cancer progression and stress response. Recent studies have …
processes, including cancer progression and stress response. Recent studies have …
MT1G, an emerging ferroptosis‐related gene: A novel prognostic biomarker and indicator of immunotherapy sensitivity in prostate cancer
B Cheng, Y Lai, H Huang, S Peng… - Environmental …, 2024 - Wiley Online Library
Background Prostate cancer is a leading cause of cancer‐related deaths in men worldwide.
Despite advances in treatment strategies, there is still a need for novel therapeutic targets …
Despite advances in treatment strategies, there is still a need for novel therapeutic targets …
The key cellular senescence related molecule RRM2 regulates prostate cancer progression and resistance to docetaxel treatment
B Cheng, L Li, Y Wu, T Luo, C Tang, Q Wang, Q Zhou… - Cell & Bioscience, 2023 - Springer
Background Prostate cancer is a leading cause of cancer-related deaths among men
worldwide. Docetaxel chemotherapy has proven effective in improving overall survival in …
worldwide. Docetaxel chemotherapy has proven effective in improving overall survival in …
Interplay of Ferroptosis and Cuproptosis in Cancer: Dissecting Metal-Driven Mechanisms for Therapeutic Potentials
J Wang, J Li, J Liu, KY Chan, HS Lee, KN Lin… - Cancers, 2024 - mdpi.com
Simple Summary In the complex world of cancer, iron and copper play essential roles as
trace metal ions that are crucial for cancer cell survival. Disruption in their metabolic …
trace metal ions that are crucial for cancer cell survival. Disruption in their metabolic …
Cuproptosis, the novel type of oxidation-induced cell death in thoracic cancers: can it enhance the success of immunotherapy?
R Zhao, O Sukocheva, E Tse, M Neganova… - Cell Communication and …, 2024 - Springer
Copper is an important metal micronutrient, required for the balanced growth and normal
physiological functions of human organism. Copper-related toxicity and dysbalanced …
physiological functions of human organism. Copper-related toxicity and dysbalanced …
Systematic analysis based on the cuproptosis-related genes identifies ferredoxin 1 as an immune regulator and therapeutic target for glioblastoma
L Dai, P Zhou, L Lyu, S Jiang - BMC cancer, 2023 - Springer
Glioblastoma multiforme (GBM) is recognized as the prevailing malignant and aggressive
primary brain tumor, characterized by an exceedingly unfavorable prognosis. Cuproptosis, a …
primary brain tumor, characterized by an exceedingly unfavorable prognosis. Cuproptosis, a …
Prostate cancer microenvironment: multidimensional regulation of immune cells, vascular system, stromal cells, and microbiota
L Chen, YX Xu, YS Wang, YY Ren, XM Dong, P Wu… - Molecular Cancer, 2024 - Springer
Prostate cancer (PCa) is one of the most prevalent malignancies in males worldwide.
Increasing research attention has focused on the PCa microenvironment, which plays a …
Increasing research attention has focused on the PCa microenvironment, which plays a …
[HTML][HTML] Expanding horizons in overcoming therapeutic resistance in castration-resistant prostate cancer: targeting the androgen receptor-regulated tumor immune …
B Cheng, H Huang - Cancer Biology & Medicine, 2023 - ncbi.nlm.nih.gov
Castration-resistant prostate cancer (CRPC) poses a major treatment challenge, because
disease progression occurs despite androgen deprivation therapy (ADT) 1. Overcoming …
disease progression occurs despite androgen deprivation therapy (ADT) 1. Overcoming …
Crosstalk among mitophagy, pyroptosis, ferroptosis, and necroptosis in central nervous system injuries
L Zhang, Z Hu, Z Li, Y Lin - Neural Regeneration Research, 2024 - journals.lww.com
Central nervous system injuries have a high rate of resulting in disability and mortality;
however, at present, effective treatments are lacking. Programmed cell death, which is a …
however, at present, effective treatments are lacking. Programmed cell death, which is a …