The strategy of using existing drugs originally developed for one disease to treat other
indications has found success across medical fields. Such drug repurposing promises faster …

Increasing evidence suggests that microorganisms might represent at least highly
interesting cofactors in colorectal cancer (CRC) oncogenesis and progression. Still …

High-grade serous ovarian cancer (HGSC) is the most lethal histotype of ovarian cancer and
the majority of cases present with metastasis and late-stage disease. Over the last few …

Human endogenous retroviruses (HERV) have been implicated in a variety of diseases
including cancers. Recent research implicates HERVs in epigenetic gene regulation. Here …

Background Endoretroviruses account for circa 8% of all transposable elements found in the
genome of humans and other animals. They represent a genetic footprint of ancestral germ …

Transposable element (TE) has the ability to insert into certain parts of the genome, and due
to this event, it is possible for TEs to generate new factors and one of these factors are …

Global efforts invested in the prevention and treatment of cancer need to be repositioned to
develop safe, effective, and economic anticancer therapeutics by adopting rational …

Colon cancer is the fourth most common malignancy in both incidence and mortality in
developed countries. Infectious agents are among the risk factors for colon cancer …

Endogenous retroviruses (ERVs) are becoming more and more relevant in cancer research
and might be potential targets. The oncogenic potential of human ERVs (HERVs) has been …

The vertebrate genome contains an endogenous retrovirus that has been inherited from the
past millions of years. Although approximately 8% of human chromosomal DNA consists of …