Neurodegenerative diseases are progressive degenerative conditions characterized by the
functional deterioration and ultimate loss of neurons. These incurable and debilitating …

The levels and conformers of alpha‐synuclein are critical in the pathogenesis of Parkinson's
Disease and related synucleinopathies. Homeostatic mechanisms in protein degradation …

Photobiomodulation (PBM), also known as Low-level Laser Therapy (LLLT), involves the
use of light from a laser or light-emitting diode (LED) in the treatment of various disorders …

Synucleinopathies, including Parkinson's disease (PD), dementia with Lewy Bodies (DLB),
and multiple system atrophy (MSA), are characterized by the misfolding and subsequent …

Several lines of evidence from neuropathological studies, human genetics, in vitro
aggregation studies and cellular and animal models support the hypothesis that aSyn plays …

Misfolding and aggregation of alpha‐synuclein (α‐synuclein) with concomitant cytotoxicity is
a hallmark of Lewy body related disorders such as Parkinson's disease, dementia with Lewy …

Fibrillar aggregates of the α-synuclein (αS) protein are the hallmark of Parkinson's Disease
and related neurodegenerative disorders. Characterization of the effects of mutations and …

The nervous system spread of alpha-synuclein fibrils is thought to cause Parkinson's
disease (PD) and other synucleinopathies; however, the mechanisms underlying …

Parkinson's disease (PD) is the second most common neurodegenerative disease,
characterized by progressive bradykinesia, rigidity, resting tremor, and gait impairment, as …

The Lewy bodies and Lewy neurites are key pathological hallmarks of Parkinson's disease
(PD). Single-point mutations associated with familial PD cause α-synuclein (α-Syn) …