Normal wound healing progresses through inflammatory, proliferative and remodeling
phases in response to tissue injury. Collagen, a key component of the extracellular matrix …

The contribution of nerves to the pathogenesis of malignancies has emerged as an
important component of the tumour microenvironment. Recent studies have shown that …

Collagen type I is the main organic constituent of the bone extracellular matrix and has been
used for decades as scaffolding material in bone tissue engineering approaches when …

The structure of connective tissues including cartilage, tendons, and ligaments as well as
many organs, like the skin, heart, liver, kidney, lungs, blood vessels, and bones, depend on …

Nerves closely associate with blood vessels and help to pattern the vasculature during
development. Recent work suggests that newly formed nerve fibers may regulate the tumor …

Microvasculature functions at the tissue and cell level, regulating local mass exchange of
oxygen and nutrient-rich blood. While there has been considerable success in the …

The engineering of skin substitutes and their application on human patients has become a
reality. However, cell biologists, biochemists, technical engineers, and surgeons are still …

Background Angiogenesis is the process of neovascularization from pre-existing
vasculature and is involved in various physiological and pathological processes. Inhibitors …

One critical obstacle facing tissue engineering is the formation of functional vascular
networks that can support tissue survival in vivo. We hypothesized that prevascularizing a …

The prevention and treatment of dental caries are major challenges occurring in dentistry.
The foundations for modern management of this dental disease, estimated to affect 90% of …