Proteomic surveys with top-down platforms are today revealing thousands of naturally
occurring fragments of bigger proteins. Some of them have not functional meaning because …

Invasive fungal infections (IFIs) are increasing as major infectious diseases around the
world, and the limited efficacy of existing medications has resulted in substantial morbidity …

Candida albicans is a major cause of human infections, ranging from relatively simple to
treat skin and mucosal diseases to systemic life-threatening invasive candidiasis. Fungal …

Commensal yeast from the genus Candida is part of the healthy human microbiota. In some
cases, Candida spp. dysbiosis can result in candidiasis, the symptoms of which may vary …

Fungal infections have increased in recent decades with considerable morbidity and
mortality, mainly in immunosuppressed or admitted-to-the-ICU patients. The fungal …

Mycoses still represent relevant opportunistic infections worldwide, although overshadowed
in recent years by other severe and more widespread infections. Moreover, deep-seated …

Background/Aims: New antivirals are needed to supplement or replace currently used drugs.
The aim of this study was to evaluate the antiviral activity of synthetic peptides derived from …

Candida albicans is a commensal organism, commonly inhabiting mucosal surfaces of
healthy individuals, as a part of the resident microbiota. However, in susceptible hosts …

Antimicrobial resistance is a major public health concern worldwide. Albeit to a lesser extent
than bacteria, fungi are also becoming increasingly resistant to antifungal drugs. Moreover …

Evidence from previous works disclosed the antimicrobial, antiviral, anti-tumour and/or
immunomodulatory activity exerted, through different mechanisms of action, by peptides …