Although weight gain is a serious but variable adverse effect of antipsychotics that has
genetic underpinnings, a comprehensive meta-analysis of pharmacogenetics of …

Antipsychotic medications are critical to child and adolescent psychiatry, from the
stabilization of psychotic disorders like schizophrenia, bipolar disorder, and psychotic …

Metabolic syndrome (MetS) is a cluster of factors that increases the risk of cardiovascular
disease (CVD), one of the leading causes of mortality in patients with schizophrenia …

Objective: During the past decades, increasing efforts have been invested in studies to
unravel the influence of genetic factors on antipsychotic (AP) dosage, treatment response …

The membrane transport protein P-glycoprotein (P-gp) is an interesting candidate for
individual differences in response to antipsychotics. To present an overview of the current …

Adverse events, response failures and medication non-compliance are common in patients
receiving medications for the treatment of mental illnesses. A systematic literature review …

Genetic polymorphism in olanzapine-metabolizing enzymes, transporters and drug targets is
associated with alterations in safety and efficacy. The aim of this systematic review is to …

Background: Individuals with severe mental illness experience increased morbidity and
mortality compared to the general population. Adverse effects of antipsychotics, including …

The effectiveness of antipsychotic drugs is limited due to accompanying adverse effects
which can pose considerable health risks and lead to patient noncompliance …

Objective: Atypical antipychotics are linked to a higher incidence of metabolic side effects,
including weight gain, dyslipidemia, and diabetes. In this study, we examined the …