Consensus recommendations for a standardized Brain Tumor Imaging Protocol in clinical trials
BM Ellingson, M Bendszus, J Boxerman… - Neuro …, 2015 - academic.oup.com
A recent joint meeting was held on January 30, 2014, with the US Food and Drug
Administration (FDA), National Cancer Institute (NCI), clinical scientists, imaging experts …
Administration (FDA), National Cancer Institute (NCI), clinical scientists, imaging experts …
[HTML][HTML] Modified criteria for radiographic response assessment in glioblastoma clinical trials
Radiographic endpoints including response and progression are important for the
evaluation of new glioblastoma therapies. The current RANO criteria was developed to …
evaluation of new glioblastoma therapies. The current RANO criteria was developed to …
Malignant astrocytic glioma: genetics, biology, and paths to treatment
FB Furnari, T Fenton, RM Bachoo… - Genes & …, 2007 - genesdev.cshlp.org
Malignant astrocytic gliomas such as glioblastoma are the most common and lethal
intracranial tumors. These cancers exhibit a relentless malignant progression characterized …
intracranial tumors. These cancers exhibit a relentless malignant progression characterized …
Pseudoprogression, radionecrosis, inflammation or true tumor progression? Challenges associated with glioblastoma response assessment in an evolving …
The wide variety of treatment options that exist for glioblastoma, including surgery, ionizing
radiation, anti-neoplastic chemotherapies, anti-angiogenic therapies, and active or passive …
radiation, anti-neoplastic chemotherapies, anti-angiogenic therapies, and active or passive …
Advances in the knowledge of the molecular biology of glioblastoma and its impact in patient diagnosis, stratification, and treatment
B Delgado‐Martín, MÁ Medina - Advanced Science, 2020 - Wiley Online Library
Gliomas are the most common primary brain tumors in adults. They arise in the glial tissue
and primarily occur in the brain. Low‐grade tumors of World Health Organization (WHO) …
and primarily occur in the brain. Low‐grade tumors of World Health Organization (WHO) …
Fluorescein-guided surgery for resection of high-grade gliomas: a multicentric prospective phase II study (FLUOGLIO)
F Acerbi, M Broggi, KM Schebesch, J Höhne… - Clinical Cancer …, 2018 - AACR
Purpose: Sodium fluorescein is a dye that, intravenously injected, selectively accumulates in
high-grade glioma (HGG) tissue through a damaged blood–brain barrier. In this article, the …
high-grade glioma (HGG) tissue through a damaged blood–brain barrier. In this article, the …
Neural stem cells and the origin of gliomas
N Sanai, A Alvarez-Buylla… - New England Journal of …, 2005 - Mass Medical Soc
Little progress has been made in the treatment of gliomas during the past 25 years. One
reason is our poor understanding of the cell of origin in these tumors and of the mechanisms …
reason is our poor understanding of the cell of origin in these tumors and of the mechanisms …
Making a tumour's bed: glioblastoma stem cells and the vascular niche
RJ Gilbertson, JN Rich - Nature Reviews Cancer, 2007 - nature.com
Parallel to the role that normal stem cells play in organogenesis, cancer stem cells are
thought to be crucial for tumorigenesis. Understanding normal development might therefore …
thought to be crucial for tumorigenesis. Understanding normal development might therefore …
Molecular pathology of malignant gliomas
DN Louis - Annu. Rev. Pathol. Mech. Dis., 2006 - annualreviews.org
Malignant gliomas, the most common type of primary brain tumor, are a spectrum of tumors
of varying differentiation and malignancy grades. These tumors may arise from neural stem …
of varying differentiation and malignancy grades. These tumors may arise from neural stem …
Glial tumor grading and outcome prediction using dynamic spin-echo MR susceptibility mapping compared with conventional contrast-enhanced MR: confounding …
BACKGROUND AND PURPOSE: The MR imaging characteristics of oligodendrogliomas
and astrocytomas on spin-echo (SE), echo-planar relative cerebral blood volume (rCBV) …
and astrocytomas on spin-echo (SE), echo-planar relative cerebral blood volume (rCBV) …