Since the identification in 1988 of bone morphogenetic protein 2 (BMP2) as a potent inducer
of bone and cartilage formation, BMP superfamily signalling has become one of the most …

Bone morphogenetic proteins (BMPs) constitute the largest subdivision of the transforming
growth factor-β family of ligands. BMPs exhibit widespread utility and pleiotropic, context …

Bone morphogenetic proteins (BMPs) are cytokines belonging to the transforming growth
factor-β (TGF-β) superfamily. They play multiple functions during development and tissue …

The bone-regenerative potentials of the periosteum have been explored as early as the 17th
century. Over the past few years, however, much has been discovered in terms of the …

The treatment of large-area bone defects still faces many difficulties and challenges. Here,
we developed a blood clot delivery platform loaded with BMP-2 protein (BMP-2@ BC) for …

In this study we investigated if Wnt/β-catenin signaling in mesenchymal progenitor cells
plays a role in bone fracture repair and if DKK1-Ab promotes fracture healing through …

Endochondral ossification plays a key role in the bone healing process, which requires
normal cartilage callus formation. Progranulin (PGRN) growth factor is known to enhance …

Endochondral bone formation is an important pathway in fracture healing, involving the
formation of a cartilaginous soft callus and the process of cartilage-to-bone transition. Failure …

Bone fractures are a widespread clinical event due to accidental falls and trauma or bone
fragility; they also occur in association with various diseases and are common with aging. In …

Erythropoietin is essential for bone marrow erythropoiesis and erythropoietin receptor on
non-erythroid cells including bone marrow stromal cells suggests systemic effects of …