Collagen occurs in nature with a dedicated triple helix structure and is the most preferred
biomaterial in commercialized medical products. However, concerns on purity, disease …

Vascularization is among the top challenges that impede the clinical application of
engineered tissues. This challenge has spurred tremendous research endeavor, defined as …

Natural animal collagen and its recombinant collagen are favourable replacements in
human tissue engineering due to their remarkable biomedical property. However, this …

Growth factors (GF) are critical cytokines in wound healing. However, the direct delivery of
these biochemical cues into a wound site significantly increases the cost of wound dressings …

Background: Timely endothelial repair after intervention-associated vascular injury is critical
to prevent restenosis and thrombosis. Compared to living cell therapies, exosomes may be a …

The hydrogels of natural extracellular matrix (ECM) are excellent biomaterials with
promising applications in the physiological manufacture of three-dimensional (3D) …

Bacterial systems, especially using Escherichia coli, provide a useful system for recombinant
production of collagen and collagen-like proteins. These systems provide high yields of …

Collagen, a key component of extracellular matrix serves as a linchpin for maintaining
structural integrity and functional resilience. Concerns over purity and immunogenicity of …

The promotion of vascularization and angiogenesis in the grafts is a crucial phenomenon in
the healing process and tissue engineering. It has been shown that stem cells, especially …

Achieving graft endothelialization following implantation continues to be a challenge in the
development of “off-the-shelf,” small-caliber, arterial prostheses. Coating grafts with …