The fast-growing field of photo-driven theranostics based on aggregation-induced emission

Z Zhang, M Kang, H Tan, N Song, M Li, P Xiao… - Chemical Society …, 2022 - pubs.rsc.org
Photo-driven theranostics, also known as phototheranostics, relying on the diverse excited-
state energy conversions of theranostic agents upon photoexcitation represents a significant …

Aggregation-induced emission photosensitizer-based photodynamic therapy in cancer: from chemical to clinical

Z Meng, H Xue, T Wang, B Chen, X Dong… - Journal of …, 2022 - Springer
Cancer remains a serious threat to human health owing to the lack of effective treatments.
Photodynamic therapy (PDT) has emerged as a promising non-invasive cancer treatment …

Brain co‐delivery of temozolomide and cisplatin for combinatorial glioblastoma chemotherapy

Y Zou, Y Wang, S Xu, Y Liu, J Yin… - Advanced …, 2022 - Wiley Online Library
Glioblastoma (GBM) is an intractable malignancy with high recurrence and mortality.
Combinatorial therapy based on temozolomide (TMZ) and cisplatin (CDDP) shows …

Improving image‐guided surgical and immunological tumor treatment efficacy by photothermal and photodynamic therapies based on a multifunctional NIR AIEgen

R Jiang, J Dai, X Dong, Q Wang, Z Meng… - Advanced …, 2021 - Wiley Online Library
Multimodal therapy is attracting increasing attention to improve tumor treatment efficacy, but
generally requires various complicated ingredients combined within one theranostic system …

9, 10-Phenanthrenequinone: a promising kernel to develop multifunctional antitumor systems for efficient type I photodynamic and photothermal synergistic therapy

J Guo, J Dai, X Peng, Q Wang, S Wang, X Lou, F Xia… - ACS …, 2021 - ACS Publications
Synergistic phototherapy provides a promising strategy to conquer the hypoxia and
heterogeneity of tumors and realize a better therapeutic effect than monomodal …

Adjuvant physiochemistry and advanced nanotechnology for vaccine development

H Ren, W Jia, Y Xie, M Yu, Y Chen - Chemical Society Reviews, 2023 - pubs.rsc.org
Vaccines comprising innovative adjuvants are rapidly reaching advanced translational
stages, such as the authorized nanotechnology adjuvants in mRNA vaccines against COVID …

Carrier-free nano-PROTACs to amplify photodynamic therapy induced DNA damage through BRD4 degradation

LP Zhao, XN Rao, RR Zheng, CY Huang, RJ Kong… - Nano Letters, 2023 - ACS Publications
Therapy-induced DNA damage is the most common strategy to inhibit tumor cell
proliferation, but the therapeutic efficacy is limited by DNA repair machinery. Carrier-free …

Nano-ROS-generating approaches to cancer dynamic therapy: lessons from nanoparticles

Q Zhang, Q Luo, Z Liu, M Sun, X Dong - Chemical Engineering Journal, 2023 - Elsevier
Reactive oxygen species (ROS)-based dynamic cancer therapies are therapeutic modalities
of endogenous/exogenous-responsive intratumoral ROS generation, including …

Tailoring the amphiphilic structure of zwitterionic AIE photosensitizers to boost antitumor immunity

T Zhang, X Yang, X Ou, MMS Lee, J Zhang… - Advanced …, 2023 - Wiley Online Library
Although photodynamic therapy (PDT) for thorough cancer treatment is hindered by the
limited generation of reactive oxygen species (ROS) with short lifetime from …

Research progress on AIE cyanostilbene-based self-assembly gels: Design, regulation and applications

A Gao, Q Wang, H Wu, JW Zhao, X Cao - Coordination Chemistry Reviews, 2022 - Elsevier
Aggregation-induced emission (AIE) is attracting enormous attention due to the immense
potential practical application of luminescent materials in the solid state. Cyanostilbene …