Peptidomics is the comprehensive characterization of peptides from biological sources
instead of heading for a few single peptides in former peptide research. Mass spectrometry …

BACKGROUND Cerebrospinal fluid (CSF) tau is a common biomarker for Alzheimer disease
(AD). Measurements of tau have historically been performed using immunoassays. Given …

Introduction: In the last decade, our increased knowledge of factors governing the
pharmacokinetics and metabolism of biologics (recombinant therapeutic proteins) has …

Nanoparticle-mediated sustained delivery of therapeutics is one of the highly effective and
increasingly utilized applications of nanomedicine. Here, we report the development and …

Background Numerous immunoassays have been developed to quantify amyloid β1-40
(Aβ40) and amyloid β1-42 (Aβ42). Nevertheless, given the low concentration of Aβ and the …

Apelin, the endogenous ligand for the APJ receptor, has generated interest due to its
beneficial effects on the cardiovascular system. Synthesized as a 77 amino acid …

Aim: Patients with elevated levels of B-type natriuretic peptide (BNP) and/or NT-proBNP as
measured by clinical tests have an elevated risk of heart failure (HF). Despite utility in large …

Background: Enterovirus 71 (EV71) infection serves as a leading cause of hand-foot-and-
mouth disease, and induces neural disorders. Apelin-13, as a neuropeptide, presents …

BWVPHIKGXQBZPV-QKFDDRBGSA-N Apelin Chemical compound NCC (= O) N [C@@
H](CO) C (= O) N [C@@ H](CC (C) C) C (= O) N [C@@ H](CCSC) C (= O) N1CCC [C@ H] …

A krónikus szívelégtelenség gyakori betegség, mely az életminőséget jelentősen rontja, a
halálozást növeli, valamint óriási terhet tesz a társadalom vállára (1). A fejlett országokban a …