Intrahost evolution of the gut microbiota

HC Barreto, I Gordo - Nature Reviews Microbiology, 2023 - nature.com
A massive number of microorganisms, belonging to different species, continuously divide
inside the guts of animals and humans. The large size of these communities and their rapid …

[HTML][HTML] Perspective: leveraging the gut microbiota to predict personalized responses to dietary, prebiotic, and probiotic interventions

SM Gibbons, T Gurry, JW Lampe, A Chakrabarti… - Advances in …, 2022 - Elsevier
Humans often show variable responses to dietary, prebiotic, and probiotic interventions.
Emerging evidence indicates that the gut microbiota is a key determinant for this population …

[HTML][HTML] Linear and nonlinear correlation estimators unveil undescribed taxa interactions in microbiome data

H Lin, M Eggesbø, SD Peddada - Nature communications, 2022 - nature.com
It is well-known that human gut microbiota form an ecosystem where microbes interact with
each other. Due to complex underlying interactions, some microbes may correlate …

Network analyses in microbiome based on high-throughput multi-omics data

Z Liu, A Ma, E Mathé, M Merling, Q Ma… - Briefings in …, 2021 - academic.oup.com
Together with various hosts and environments, ubiquitous microbes interact closely with
each other forming an intertwined system or community. Of interest, shifts of the relationships …

Data-driven causal analysis of observational biological time series

AE Yuan, W Shou - Elife, 2022 - elifesciences.org
Complex systems are challenging to understand, especially when they defy manipulative
experiments for practical or ethical reasons. Several fields have developed parallel …

A primer for microbiome time-series analysis

AR Coenen, SK Hu, E Luo, D Muratore… - Frontiers in genetics, 2020 - frontiersin.org
Time-series can provide critical insights into the structure and function of microbial
communities. The analysis of temporal data warrants statistical considerations, distinct from …

Inferring species interactions using Granger causality and convergent cross mapping

F Barraquand, C Picoche, M Detto, F Hartig - Theoretical Ecology, 2021 - Springer
Identifying directed interactions between species from time series of their population
densities has many uses in ecology. This key statistical task is equivalent to causal time …

Engineering the microbiome to prevent adverse events: challenges and opportunities

S Khan, R Hauptman, L Kelly - Annual review of pharmacology …, 2021 - annualreviews.org
In the past decade of microbiome research, we have learned about numerous adverse
interactions between the microbiome and medical interventions such as drugs, radiation …

Methodological Considerations in Longitudinal Analyses of Microbiome Data: A Comprehensive Review

R Lyu, Y Qu, K Divaris, D Wu - Genes, 2023 - mdpi.com
Biological processes underlying health and disease are inherently dynamic and are best
understood when characterized in a time-informed manner. In this comprehensive review …

The diagnostic potential and barriers of microbiome based therapeutics

A Acharjee, U Singh, SP Choudhury, GV Gkoutos - Diagnosis, 2022 - degruyter.com
High throughput technological innovations in the past decade have accelerated research
into the trillions of commensal microbes in the gut. The 'omics' technologies used for …