Bioinorganic chemistry of Alzheimer's disease

KP Kepp - Chemical reviews, 2012 - ACS Publications
Alzheimer's disease (AD) 1− 3 is the most common form of dementia (estimated∼ 50− 60%
of all cases), associated with loss of memory (in particular episodic memory), cognitive …

Systematic review of potential health risks posed by pharmaceutical, occupational and consumer exposures to metallic and nanoscale aluminum, aluminum oxides …

CC Willhite, NA Karyakina, RA Yokel… - Critical reviews in …, 2014 - Taylor & Francis
Aluminum (Al) is a ubiquitous substance encountered both naturally (as the third most
abundant element) and intentionally (used in water, foods, pharmaceuticals, and vaccines); …

Extraction of iron (III) ions by core-shell microgel for in situ formation of iron nanoparticles to reduce harmful pollutants from water

M Arif - Journal of Environmental Chemical Engineering, 2023 - Elsevier
Since the most transition metal ions and organic dyes are hazardous, it is crucial to remove
them from water. For this purpose, various systems are reported for removal of only transition …

Copper oxide nanoparticles: In vitro and in vivo toxicity, mechanisms of action and factors influencing their toxicology

H Sajjad, A Sajjad, RT Haya, MM Khan, M Zia - … and Physiology Part C …, 2023 - Elsevier
Abstract Copper oxide nanoparticles (CuO NPs) have received increasing interest due to
their distinctive properties, including small particle size, high surface area, and reactivity …

Air pollution, glymphatic impairment, and Alzheimer's disease

R Hussain, U Graham, A Elder, M Nedergaard - Trends in Neurosciences, 2023 - cell.com
Epidemiological evidence demonstrates a link between air pollution exposure and the onset
and progression of cognitive impairment and Alzheimer's disease (AD). However, current …

Low levels of aluminum can lead to behavioral and morphological changes associated with Alzheimer's disease and age-related neurodegeneration

SC Bondy - Neurotoxicology, 2016 - Elsevier
Aluminum (Al) is a very common component of the earth's mineral composition. It is not
essential element for life and is a constituent of rather inert minerals. Therefore, it has often …

Role of copper in the onset of Alzheimer's disease compared to other metals

S Bagheri, R Squitti, T Haertlé, M Siotto… - Frontiers in aging …, 2018 - frontiersin.org
Alzheimer's disease (AD) is a neurodegenerative disorder that is characterized by amyloid
plaques in patients' brain tissue. The plaques are mainly made of β-amyloid peptides and …

Neurotoxic effects of aluminium exposure as a potential risk factor for Alzheimer's disease

M Dey, RK Singh - Pharmacological Reports, 2022 - Springer
Aluminium is one of the most widely distributed elements of the Earth's crust. Its routine use
has resulted in excessive human exposure and due to the potential neurotoxic effects has …

Revisiting the intersection of amyloid, pathologically modified tau and iron in Alzheimer's disease from a ferroptosis perspective

PJ Derry, ML Hegde, GR Jackson, R Kayed… - Progress in …, 2020 - Elsevier
The complexity of Alzheimer's disease (AD) complicates the search for effective treatments.
While the key roles of pathologically modified proteins has occupied a central role in …

The role of metallobiology and amyloid‐β peptides in Alzheimer's disease

BR Roberts, TM Ryan, AI Bush… - Journal of …, 2012 - Wiley Online Library
J. Neurochem.(2012) 120 (Suppl. 1), 149–166. Abstract The biggest risk factor for
Alzheimer's disease is the process of ageing, but the mechanisms that lead to the …