Computational approaches for prioritizing candidate disease genes based on PPI networks
With the continuing development and improvement of genome-wide techniques, a great
number of candidate genes are discovered. How to identify the most likely disease genes …
number of candidate genes are discovered. How to identify the most likely disease genes …
Computational disease gene prioritization: an appraisal
N Gill, S Singh, TC Aseri - Journal of Computational Biology, 2014 - liebertpub.com
Bioinformatics aids in the understanding of the biological processes of living beings and the
genetic architecture of human diseases. The discovery of disease-related genes improves …
genetic architecture of human diseases. The discovery of disease-related genes improves …
Network-based ranking methods for prediction of novel disease associated microRNAs
DH Le - Computational Biology and Chemistry, 2015 - Elsevier
Background Many studies have shown roles of microRNAs on human disease and a
number of computational methods have been proposed to predict such associations by …
number of computational methods have been proposed to predict such associations by …
Diverse type 2 diabetes genetic risk factors functionally converge in a phenotype-focused gene network
Type 2 Diabetes (T2D) constitutes a global health burden. Efforts to uncover predisposing
genetic variation have been considerable, yet detailed knowledge of the underlying …
genetic variation have been considerable, yet detailed knowledge of the underlying …
In Silico Analysis of the Effect of Hydrastis canadensis on Controlling Breast Cancer
H Vyshnavi AM, S Sankaran, K Namboori PK… - Medicina, 2023 - mdpi.com
Background and Objectives: Breast cancer is a significant type of cancer among women
worldwide. Studies have reported the anti-carcinogenic activity of Hydrastis Canadensis …
worldwide. Studies have reported the anti-carcinogenic activity of Hydrastis Canadensis …
Bioinformatics tools for the functional interpretation of quantitative proteomics results
T Nunez Villavicencio-Diaz… - Current topics in …, 2014 - ingentaconnect.com
Proteins are the principal mediators of the functions in the cell; therefore, any abnormal
variations on their abundance levels may reflect the presence of pathological processes. In …
variations on their abundance levels may reflect the presence of pathological processes. In …
[PDF][PDF] A leader genes approach-based tool for molecular genomics: from gene-ranking to gene-network systems biology and biotargets predictions
NL Bragazzi, C Nicolini - J Comput Sci Syst Biol, 2013 - researchgate.net
Nanogenomics, being the interplay of nanobiotechnologies and bioinformatics, is emerging
as an intriguing approach in the field of nowadays biomedicine. Microarrays can produce a …
as an intriguing approach in the field of nowadays biomedicine. Microarrays can produce a …
Profiling, bioinformatic, and functional data on the developing olfactory/GnRH system reveal cellular and molecular pathways essential for this process and potentially …
G Garaffo, P Provero, I Molineris, P Pinciroli… - Frontiers in …, 2013 - frontiersin.org
During embryonic development, immature neurons in the olfactory epithelium (OE) extend
axons through the nasal mesenchyme, to contact projection neurons in the olfactory bulb …
axons through the nasal mesenchyme, to contact projection neurons in the olfactory bulb …
Applications of random walk model on biological networks
Biological networks play a significant role in addressing biological problems. Random walk
model is a highly efficient way to study networks which has been widely used in solving …
model is a highly efficient way to study networks which has been widely used in solving …
NECorr, a tool to rank gene importance in biological processes using molecular networks and transcriptome data
The challenge of increasing crop yield while decreasing plants' susceptibility to various
stresses can be lessened by understanding plant regulatory processes in a tissue-specific …
stresses can be lessened by understanding plant regulatory processes in a tissue-specific …