The interactions between obesity and infectious diseases have recently received increasing
recognition as emerging data have indicated an association between obesity and poor …

The prevalence of obesity has dramatically increased in recent years and now includes a
significant proportion of the world's children, adolescents and adults. Obesity is linked to a …

Background: Previous evidence-based guidelines on the management of intra-abdominal
infection (IAI) were published by the Surgical Infection Society (SIS) in 1992, 2002, and …

Obesity causes a number of changes, including an increase in volume of distribution and
changes in hepatic metabolism and renal excretion. Several antibiotics have sufficient data …

Severe sepsis and septic shock can alter the pharmacokinetics of broad-spectrum β-lactams
(meropenem, ceftazidime/cefepime, and piperacillin-tazobactam), resulting in inappropriate …

Bariatric surgery for obesity has emerged as an effective and commonly used treatment
modality. This paper reviews the surgical site infections (SSIs) that occur post bariatric …

Importance of the field: Piperacillin-tazobactam is a frequently prescribed intravenous
antibiotic for moderate to severe infections used in hospital settings because of its broad …

Background The prevention of healthcare-associated infections (HCAIs) is a major goal in
modern healthcare. Intrinsic, patient-related factors may contribute to the risk of HCAIs. Aim …

Though we know much about development of obesity and its associated complications like
type II diabetes, cardiovascular diseases, hypertension and cancer, our knowledge is very …

The study objective was to evaluate the population pharmacokinetics and
pharmacodynamics of piperacillin and tazobactam administered by prolonged infusion in …