Why do viruses cause cancer? Highlights of the first century of human tumour virology

PS Moore, Y Chang - Nature reviews cancer, 2010 - nature.com
The year 2011 marks the centenary of Francis Peyton Rous's landmark experiments on an
avian cancer virus. Since then, seven human viruses have been found to cause 10–15% of …

Molecular genetics of Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) epidemiology and pathogenesis

LA Dourmishev, AL Dourmishev… - Microbiology and …, 2003 - Am Soc Microbiol
Kaposi's sarcoma had been recognized as unique human cancer for a century before it
manifested as an AIDS-defining illness with a suspected infectious etiology. The discovery of …

Molecular biology of Kaposi's sarcoma-associated herpesvirus and related oncogenesis

Q Cai, SC Verma, J Lu, ES Robertson - Advances in virus research, 2010 - Elsevier
Abstract Kaposi's Sarcoma-associated Herpesvirus (KSHV), also known as human
herpesvirus 8 (HHV-8), is the most recently identified human tumor virus, and is associated …

Kaposi's sarcoma-associated herpesvirus immune modulation: an overview

SAR Rezaee, C Cunningham… - Journal of General …, 2006 - microbiologyresearch.org
Kaposi's sarcoma-associated herpesvirus (KSHV) is the most recently discovered human
herpesvirus. It is the aetiological agent of Kaposi's sarcoma (KS), a tumour frequently …

KSHV Rta promoter specification and viral reactivation

J Guito, DM Lukac - Frontiers in microbiology, 2012 - frontiersin.org
Viruses are obligate intracellular pathogens whose biological success depends upon
replication and packaging of viral genomes, and transmission of progeny viruses to new …

Functional p53 signaling in Kaposi's sarcoma-associated herpesvirus lymphomas: implications for therapy

CE Petre, SH Sin, DP Dittmer - Journal of virology, 2007 - Am Soc Microbiol
The Kaposi's sarcoma-associated herpesvirus (KSHV/HHV8) is associated with Kaposi's
sarcoma (KS) as well as primary effusion lymphomas (PEL). The expression of viral proteins …

The role of Kaposi's sarcoma-associated herpesvirus/human herpesvirus-8 regulator of transcription activation (RTA) in control of gene expression

JT West, C Wood - Oncogene, 2003 - nature.com
The mechanisms that control the replication state, latency versus lytic, of human
herpesviruses have been under intense investigations. Here we summarize some of the …

Molecular biology of KSHV in relation to AIDS-associated oncogenesis

W Greene, K Kuhne, F Ye, J Chen, F Zhou… - Aids-Associated Viral …, 2007 - Springer
In 1872, the famed Hungarian dermatologist Moritz Kaposi characterized an “idiopathic
multiple pigmented sarcoma” which is now known as Kaposi's sarcoma (KS). 424 For most …

[HTML][HTML] Amplification of the Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8 lytic origin of DNA replication is dependent upon a cis-acting AT-rich …

DP AuCoin, KS Colletti, SA Cei, I Papousková… - Virology, 2004 - Elsevier
Kaposi's sarcoma-associated herpesvirus (KSHV), also known as human herpesvirus 8
(HHV8), has significant sequence homology to Epstein–Barr virus (EBV). In cell culture …

Epigenetic mechanisms in virus-induced tumorigenesis

E Poreba, JK Broniarczyk, A Gozdzicka-Jozefiak - Clinical epigenetics, 2011 - Springer
Abstract About 15–20% of human cancers worldwide have viral etiology. Emerging data
clearly indicate that several human DNA and RNA viruses, such as human papillomavirus …