Cell-based cardiac repair offers the promise of rebuilding the injured heart from its
component parts. Work began with committed cells such as skeletal myoblasts, but recently …

Stem cells represent natural units of embryonic development and tissue regeneration.
Embryonic stem (ES) cells, in particular, possess a nearly unlimited self-renewal capacity …

This paper is the 28th consecutive installment of the annual review of research concerning
the endogenous opioid system, now spanning over a quarter-century of research. It …

Side population (SP) cells, which can be identified by their ability to exclude Hoechst 33342
dye, are one of the candidates for somatic stem cells. Although bone marrow SP cells are …

Angiotensin II (Ang II) has a significant role in regulating cardiac homeostasis through
humoral, autocrine and paracrine pathways, via binding to the plasma membrane AT1 …

Potential applications of stem cells in medicine range from their inclusion in disease
modeling and drug discovery to cell transplantation and regenerative therapies. However …

Human adipose-derived stem cells (hASCs) have been recently proposed as a suitable tool
for regenerative therapies for their simple isolation procedure and high proliferative …

Modulation of stem cell differentiation is an important assignment for cellular engineering.
Embryonic stem (ES) cells can differentiate into cardiomyocytes, but the efficiency is typically …

Opioid peptide receptor (OPR) and β-adrenergic receptor (β-AR) are well-established
members of G-protein-coupled receptor (GPCR) superfamily and are involved in regulating …

Somatic cells can be directly reprogrammed to alternative differentiated fates without first
becoming stem/progenitor cells. Nevertheless, the initial need for viral-mediated gene …