Quantitative spinal cord (SC) magnetic resonance imaging (MRI) presents many challenges,
including a lack of standardized imaging protocols. Here we present a prospectively …

Objectives Currently, multiple sclerosis is treated with anti-inflammatory therapies, but these
treatments lack efficacy in progressive disease. New treatment strategies aim to repair …

Rapid and efficient transmission of electric signals among neurons of vertebrates is ensured
by myelin‐insulating sheaths surrounding axons. Human cognition, sensation, and motor …

Myelin is the protective sheath wrapped around axons, consisting of a phospholipid bilayer
with water between the wraps. The measurement of damage to the myelin sheaths, the …

Tremendous efforts have been made in the last decade to advance cutting-edge MRI
technology in pursuit of mapping structural connectivity in the living human brain with …

Background The g-ratio, quantifying the comparative thickness of the myelin sheath
encasing an axon, is a geometrical invariant that has high functional relevance because of …

In vivo histology using magnetic resonance imaging (MRI) is a newly emerging research
field that aims to non-invasively characterize tissue microstructure. The implications of in …

Spinal cord magnetic resonance imaging (MRI) has a central role in multiple sclerosis (MS)
clinical practice for diagnosis and disease monitoring. Advanced MRI sequences capable of …

Diffusion magnetic resonance imaging (dMRI) proved promising in patients with non-
myelopathic degenerative cervical cord compression (NMDCCC), ie, without clinically …

Multi-compartment tissue modeling using diffusion magnetic resonance imaging has proven
valuable in the brain, offering novel indices sensitive to the tissue microstructural …