Standard follow-up and symptomatic treatment have allowed most patients with cystic
fibrosis to live to young adulthood. However, many patients still die prematurely from …

The interplay between airway inflammation and infection is now recognized as a major
factor in the pathobiology in cystic fibrosis (CF). A proinflammatory environment is seen …

Staphylococcus aureus (SA) is the major colonizer of the lungs of cystic fibrosis (CF) patients
during childhood and adolescence. As patients age, the prevalence of SA decreases and …

Cystic fibrosis (CF) is a common heritable genetic disorder caused by a defect in the cystic
fibrosis conductance regulator gene, resulting in several complications in the human body …

Pseudomonas aeruginosa and Staphylococcus aureus are two of the most prevalent
respiratory pathogens in cystic fibrosis patients. Both organisms often cause chronic and …

Background: Lumacaftor/ivacaftor (LUM/IVA) has shown modest benefits in previous
research, but the exact effects in the cystic fibrosis (CF) lung remain unclear. This study aims …

Improved treatments for cystic fibrosis allow more patients to become parents. This article
presents a systematic review of literature on cystic fibrosis patients' experience of …

Aim: To investigate the role of pre-established Staphylococcus aureus on Pseudomonas
aeruginosa adaptation and antibiotic tolerance. Materials & methods: Bacteria were cultured …

Cystic fibrosis (CF) is a common multi-system genetically inherited condition, predominately
found in individuals of Caucasian decent. Since the identification of the cystic fibrosis (CF) …

The study of the respiratory microbiota has revealed that the lungs of healthy and diseased
individuals harbour distinct microbial communities. Imbalances in these communities can …