Since the concept and operational definition of “cognitive frailty”(simultaneous presence of
physical frailty and cognitive impairment without concurrent dementia) were proposed by the …

The renin–angiotensin system (RAS) was initially considered to be part of the endocrine
system regulating water and electrolyte balance, systemic vascular resistance, blood …

Cerebral small vessel disease (CSVD) is a generic term used for intracranial vascular
disorders caused by the structural changes of cerebral microvessels, including the small …

Intrinsic capacity is the sum of an individual's physical and mental capacities, which helps
determine functional ability. Intrinsic capacity decline is an important predictor of adverse …

The aim of the present study was to examine the effects of a high-dose omega-3 and omega-
6 fatty acids supplementation, in combination with antioxidant vitamins, on cognitive function …

Approximately 89% of patients with Parkinson's disease (PD) suffer from dysarthria. Lee
Silverman Voice Treatment (LSVT), a behavioral therapy, aims to improve speech and voice …

In this era of unprecedented longevity, healthy aging is an important public health priority.
Avoiding or shortening the period of disability or dementia before death is critical to …

While physical frailty has been recognized as a clinical entity for some time, the concept of
cognitive frailty (CF) is now gaining increasing attention in the geriatrics research …

Constipation is Associated with Development of Cognitive Impairment in de novo Parkinson’s
Disease: A Longitudinal Analysis of Two International Cohorts - IOS Press You are viewing a …

Introduction Frailty and impaired cognitive functioning often co-occur in older adults and are
associated with adverse health outcomes. However, their relationship is unclear. This study …