Effects of air pollution on the nervous system and its possible role in neurodevelopmental and neurodegenerative disorders

LG Costa, TB Cole, K Dao, YC Chang, J Coburn… - Pharmacology & …, 2020 - Elsevier
Recent extensive evidence indicates that air pollution, in addition to causing respiratory and
cardiovascular diseases, may also negatively affect the brain and contribute to central …

Inflammatory effects of particulate matter air pollution

RD Arias-Pérez, NA Taborda, DM Gómez… - … Science and Pollution …, 2020 - Springer
Air pollution is an important cause of non-communicable diseases globally with particulate
matter (PM) as one of the main air pollutants. PM is composed of microscopic particles that …

[HTML][HTML] Pollution from fossil-fuel combustion is the leading environmental threat to global pediatric health and equity: Solutions exist

F Perera - International journal of environmental research and …, 2018 - mdpi.com
Fossil-fuel combustion by-products are the world's most significant threat to children's health
and future and are major contributors to global inequality and environmental injustice. The …

Climate change, environment pollution, COVID-19 pandemic and mental health

D Marazziti, P Cianconi, F Mucci, L Foresi… - Science of the total …, 2021 - Elsevier
Converging data would indicate the existence of possible relationships between climate
change, environmental pollution and epidemics/pandemics, such as the current one due to …

Air pollution, ultrafine particles, and your brain: are combustion nanoparticle emissions and engineered nanoparticles causing preventable fatal neurodegenerative …

L Calderón-Garcidueñas, A Ayala - Environmental science & …, 2022 - ACS Publications
Exposure to particulate matter (PM) pollution damages the human brain. Fossil fuel burning
for transportation energy accounts for a significant fraction of urban air and climate pollution …

[HTML][HTML] Neurovascular dysfunction and neurodegeneration in dementia and Alzheimer's disease

AR Nelson, MD Sweeney, AP Sagare… - Biochimica et Biophysica …, 2016 - Elsevier
Vascular insults can initiate a cascade of molecular events leading to neurodegeneration,
cognitive impairment, and dementia. Here, we review the cellular and molecular …

[HTML][HTML] Particulate air pollutants, APOE alleles and their contributions to cognitive impairment in older women and to amyloidogenesis in experimental models

M Cacciottolo, X Wang, I Driscoll, N Woodward… - Translational …, 2017 - nature.com
Exposure to particulate matter (PM) in the ambient air and its interactions with APOE alleles
may contribute to the acceleration of brain aging and the pathogenesis of Alzheimer's …

Homeostasis-altering molecular processes as mechanisms of inflammasome activation

A Liston, SL Masters - Nature Reviews Immunology, 2017 - nature.com
The innate immune system uses a distinct set of germline-encoded pattern recognition
receptors (PRRs) to initiate downstream inflammatory cascades. This recognition system is …

A review of the possible associations between ambient PM2. 5 exposures and the development of Alzheimer's disease

Y Shou, Y Huang, X Zhu, C Liu, Y Hu… - … and Environmental Safety, 2019 - Elsevier
PM2. 5 particles in air pollution have been widely considered associated with respiratory
and cardiovascular diseases. Recent studies have shown that PM2. 5 can also cause …

Neurotoxicity of traffic-related air pollution

LG Costa, TB Cole, J Coburn, YC Chang, K Dao… - Neurotoxicology, 2017 - Elsevier
The central nervous system is emerging as an important target for adverse health effects of
air pollution, where it may contribute to neurodevelopmental and neurodegenerative …