Publisher Summary There are two major methods for detecting Antiphospholipid (aPL)
antibodies. The first is based on a solid-phase immunoassay employing purified …

Dysregulation of lymphocyte function, accumulation of autoantibodies and defective
clearance of circulating immune complexes and apoptotic cells are hallmarks of systemic …

▪ Objective: To determine whether the presence of anticardiolipin antibodies is a risk factor
for ischemic stroke and venous thrombosis in healthy adult men.▪ Design: A nested, case …

The primary anti-phospholipid syndrome is characterized by recurrent venous and arterial
thromboembolic phenomena, recurrent fetal loss, thrombocytopenia, and serological …

Background—Antiphospholipid (aPL) antibodies are associated with thrombosis in patients
diagnosed with antiphospholipid syndrome (APS) and enhance thrombus formation in vivo …

Prothrombotic properties of antiphospholipid (aPL) antibodies may be explained in part by
their ability to enhance the activation of platelets pre-treated with low doses of ADP or …

Antiphospholipid antibodies (Abs) are associated with thrombosis and are a risk factor for
recurrent pregnancy loss and obstetric complications in patients with the antiphospholipid …

Background Previous studies have demonstrated that human monoclonal and polyclonal
anticardiolipin antibodies have thrombogenic properties in vivo. Using such a model in …

Objective To study the intracellular mechanism involved in the up‐regulation of tissue factor
(TF) on endothelial cells (ECs) by antiphospholipid antibodies (aPL), we examined the …

Haematological involvement is common in systemic lupus erythematosus (SLE). Whilst
anaemia is most often due to chronic disease, other causes such as autoimmune haemolytic …