[HTML][HTML] Biology, risk stratification, and therapy of pediatric acute leukemias: an update

CH Pui, WL Carroll, S Meshinchi… - Journal of clinical …, 2011 - ncbi.nlm.nih.gov
Purpose We review recent advances in the biologic understanding and treatment of
childhood acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML), identify …

Diagnosis and management of acute myeloid leukemia in children and adolescents: recommendations from an international expert panel

U Creutzig, MM van Den Heuvel-Eibrink… - Blood, The Journal …, 2012 - ashpublications.org
Despite major improvements in outcome over the past decades, acute myeloid leukemia
(AML) remains a life-threatening malignancy in children, with current survival rates of∼ …

The molecular landscape of pediatric acute myeloid leukemia reveals recurrent structural alterations and age-specific mutational interactions

H Bolouri, JE Farrar, T Triche Jr, RE Ries, EL Lim… - Nature medicine, 2018 - nature.com
We present the molecular landscape of pediatric acute myeloid leukemia (AML) and
characterize nearly 1,000 participants in Children's Oncology Group (COG) AML trials. The …

Donor memory-like NK cells persist and induce remissions in pediatric patients with relapsed AML after transplant

JJ Bednarski, C Zimmerman… - Blood, The Journal …, 2022 - ashpublications.org
Pediatric and young adult (YA) patients with acute myeloid leukemia (AML) who relapse
after allogeneic hematopoietic cell transplantation (HCT) have an extremely poor prognosis …

[HTML][HTML] Gemtuzumab ozogamicin in children and adolescents with de novo acute myeloid leukemia improves event-free survival by reducing relapse risk: results from …

AS Gamis, TA Alonzo, S Meshinchi, L Sung… - Journal of Clinical …, 2014 - ncbi.nlm.nih.gov
Purpose To improve survival rates in children with acute myeloid leukemia (AML), we
evaluated gemtuzumab-ozogamicin (GO), a humanized immunoconjugate targeted against …

[HTML][HTML] NKAML: a pilot study to determine the safety and feasibility of haploidentical natural killer cell transplantation in childhood acute myeloid leukemia

JE Rubnitz, H Inaba, RC Ribeiro, S Pounds… - Journal of clinical …, 2010 - ncbi.nlm.nih.gov
NKAML: A Pilot Study to Determine the Safety and Feasibility of Haploidentical Natural Killer
Cell Transplantation in Childhood Acute Myeloid Leukemia - PMC Back to Top Skip to main …

[HTML][HTML] Successes and challenges in the treatment of pediatric acute myeloid leukemia: a retrospective analysis of the AML-BFM trials from 1987 to 2012

M Rasche, M Zimmermann, L Borschel, JP Bourquin… - Leukemia, 2018 - nature.com
Overall survival (OS) of pediatric patients with acute myeloid leukemia (AML) increased in
recent decades. However, it remained unknown whether advances in first-line treatment …

Minimal residual disease-directed therapy for childhood acute myeloid leukaemia: results of the AML02 multicentre trial

JE Rubnitz, H Inaba, G Dahl, RC Ribeiro… - The lancet …, 2010 - thelancet.com
Background We sought to improve outcome in patients with childhood acute myeloid
leukaemia (AML) by applying risk-directed therapy that was based on genetic abnormalities …

Acute myeloid leukemia creates an arginase-dependent immunosuppressive microenvironment

F Mussai, C De Santo, I Abu-Dayyeh… - Blood, The Journal …, 2013 - ashpublications.org
Acute myeloid leukemia (AML) is the most common acute leukemia in adults and the second
most common frequent leukemia of childhood. Patients may present with lymphopenia or …

[HTML][HTML] Pediatric acute myeloid leukemia—past, present, and future

D Reinhardt, E Antoniou, K Waack - Journal of clinical medicine, 2022 - mdpi.com
JCM | Free Full-Text | Pediatric Acute Myeloid Leukemia—Past, Present, and Future Next
Article in Journal Sexual Habits and Sexual Dysfunctions in a Sample of Patients with Psychotic …