Formation, physiology, ecology, evolution and clinical importance of bacterial persisters
B Van den Bergh, M Fauvart… - FEMS microbiology …, 2017 - academic.oup.com
Persisters are transiently tolerant variants that allow populations to avoid eradication by
antibiotic treatment. Their antibiotic tolerance is non-genetic, not inheritable and results from …
antibiotic treatment. Their antibiotic tolerance is non-genetic, not inheritable and results from …
Horizontal gene transfer in the human gastrointestinal tract: potential spread of antibiotic resistance genes
JR Huddleston - Infection and drug resistance, 2014 - Taylor & Francis
Bacterial infections are becoming increasingly difficult to treat due to widespread antibiotic
resistance among pathogens. This review aims to give an overview of the major horizontal …
resistance among pathogens. This review aims to give an overview of the major horizontal …
Experimental design, population dynamics, and diversity in microbial experimental evolution
In experimental evolution, laboratory-controlled conditions select for the adaptation of
species, which can be monitored in real time. Despite the current popularity of such …
species, which can be monitored in real time. Despite the current popularity of such …
Mechanisms of DNA uptake by naturally competent bacteria
D Dubnau, M Blokesch - Annual review of genetics, 2019 - annualreviews.org
Transformation is a widespread mechanism of horizontal gene transfer in bacteria. DNA
uptake to the periplasmic compartment requires a DNA-uptake pilus and the DNA-binding …
uptake to the periplasmic compartment requires a DNA-uptake pilus and the DNA-binding …
Natural competence and the evolution of DNA uptake specificity
JC Mell, RJ Redfield - Journal of bacteriology, 2014 - Am Soc Microbiol
Many bacteria are naturally competent, able to actively transport environmental DNA
fragments across their cell envelope and into their cytoplasm. Because incoming DNA …
fragments across their cell envelope and into their cytoplasm. Because incoming DNA …
Cues and regulatory pathways involved in natural competence and transformation in pathogenic and environmental Gram-negative bacteria
P Seitz, M Blokesch - FEMS microbiology reviews, 2013 - academic.oup.com
Bacterial genomics is flourishing, as whole-genome sequencing has become affordable,
readily available and rapid. As a result, it has become clear how frequently horizontal gene …
readily available and rapid. As a result, it has become clear how frequently horizontal gene …
Pharmacodynamics, Population Dynamics, and the Evolution of Persistence in Staphylococcus aureus
PJT Johnson, BR Levin - PLoS genetics, 2013 - journals.plos.org
When growing populations of bacteria are confronted with bactericidal antibiotics, the vast
majority of cells are killed, but subpopulations of genetically susceptible but phenotypically …
majority of cells are killed, but subpopulations of genetically susceptible but phenotypically …
Horizontal DNA transfer mechanisms of bacteria as weapons of intragenomic conflict
Horizontal DNA transfer (HDT) is a pervasive mechanism of diversification in many microbial
species, but its primary evolutionary role remains controversial. Much recent research has …
species, but its primary evolutionary role remains controversial. Much recent research has …
Long-term industrial metal contamination unexpectedly shaped diversity and activity response of sediment microbiome
Metal contamination poses serious biotoxicity and bioaccumulation issues, affecting both
abiotic conditions and biological activity in ecosystem trophic levels, especially sediments …
abiotic conditions and biological activity in ecosystem trophic levels, especially sediments …
Self-sensing in Bacillus subtilis quorum-sensing systems
Bacterial cell–cell signalling, or quorum sensing, is characterized by the secretion and
groupwide detection of small diffusible signal molecules called autoinducers. This …
groupwide detection of small diffusible signal molecules called autoinducers. This …