Normal tissue cells are generally not viable when suspended in a fluid and are therefore
said to be anchorage dependent. Such cells must adhere to a solid, but a solid can be as …

The development of biomaterials for drug delivery, tissue engineering and medical
diagnostics has traditionally been based on new chemistries. However, there is growing …

The impact of physical and chemical modifications of nanoparticles on their biological
function has been systemically investigated and exploited to improve their circulation and …

Designing scaffolds that can mimic native skeletal muscle tissue and induce 3D cellular
alignment and elongated myotube formation remains an ongoing challenge for skeletal …

Microenvironments appear important in stem cell lineage specification but can be difficult to
adequately characterize or control with soft tissues. Naive mesenchymal stem cells (MSCs) …

Analysis of cellular mechanotransduction, the mechanism by which cells convert mechanical
signals into biochemical responses, has focused on identification of critical …

Most organs and biological tissues are soft viscoelastic materials with elastic moduli ranging
from on the order of 100 Pa for the brain to 100 000 Pa for soft cartilage. Biocompatible …

Bioimplant engineering aims to mature biological alternatives to restore, retain, or modify
damaged tissues and/or the functionality of organs. Remarkable advancements in modern …

Cardiac cells mature in the first postnatal week, concurrent with altered extracellular
mechanical properties. To investigate the effects of extracellular stiffness on cardiomyocyte …

Tissue engineering is a promising approach to repair tendon and muscle when natural
healing fails. Biohybrid constructs obtained after cells' seeding and culture in dedicated …