Background Effects of extreme sleep duration on risk of mortality and cardiovascular
outcomes remain controversial. We aimed to quantify the dose‐response relationships of …

Recent findings have deeply changed the current view of coronary heart disease, going
beyond the simplistic model of atherosclerosis as a passive process involving cholesterol …

Aims Observational studies have suggested strong associations between sleep duration
and many cardiovascular diseases (CVDs), but causal inferences have not been confirmed …

Insomnia is the most prevalent sleep disorder in the United States and has high comorbidity
with a number of cardiovascular diseases (CVDs). In the past decade, a number of …

Background There is growing evidence that sleep duration and quality may be associated
with cardiovascular harm and mortality. Methods and Results We conducted a systematic …

Study Objectives: There is limited information on the relationship between risk of
cardiovascular disease and the joint effects of sleep quality and sleep duration, especially …

Emerging evidence has assigned an important role to sleep as a modulator of metabolic
homeostasis. The impact of variations in sleep duration, sleep-disordered breathing, and …

Background National investigations on age-specific modifiable risk factor profiles for
cardiovascular disease (CVD) and mortality are scarce in China, the country that is …

Background Interest in the interplay between host genetics and the gut microbiome in
complex human diseases is increasing, with prior evidence mainly being derived from …

Background: This study examined the joint associations of sleep patterns and physical
activity with all-cause, cardiovascular disease (CVD), and cancer mortality. Methods: A total …