RNAi-based therapeutics and tumor targeted delivery in cancer
Over the past decade, non-coding RNA-based therapeutics have proven as a great potential
for the development of targeted therapies for cancer and other diseases. The discovery of …
for the development of targeted therapies for cancer and other diseases. The discovery of …
Solid lipid nanoparticles and nanostructured lipid carriers: A review emphasizing on particle structure and drug release
A Gordillo-Galeano, CE Mora-Huertas - European Journal of Pharmaceutics …, 2018 - Elsevier
Colloidal systems based on lipids have attracted attention during the last two decades as a
delivery method of drugs that are poorly soluble in water. The investigations carried out have …
delivery method of drugs that are poorly soluble in water. The investigations carried out have …
Pectin co-functionalized dual layered solid lipid nanoparticle made by soluble curcumin for the targeted potential treatment of colorectal cancer
JM Mohamed, A Alqahtani, F Ahmad… - Carbohydrate …, 2021 - Elsevier
Highlights•Dual layered solid lipid nanoparticle (DL-SLN) containing the soluble curcumin
(SC) complex investigated for the first time.•Molecular docking and interaction study of DL …
(SC) complex investigated for the first time.•Molecular docking and interaction study of DL …
Co-delivery of curcumin and Bcl-2 siRNA by PAMAM dendrimers for enhancement of the therapeutic efficacy in HeLa cancer cells
Co-delivery of therapeutic agents and small interfering RNA (siRNA) can be achieved by a
suitable nanovehicle. In this work, the solubility and bioavailability of curcumin (Cur) were …
suitable nanovehicle. In this work, the solubility and bioavailability of curcumin (Cur) were …
[HTML][HTML] Solid lipid nanoparticles: multitasking nano-carriers for cancer treatment
J German-Cortés, M Vilar-Hernández, D Rafael… - Pharmaceutics, 2023 - mdpi.com
Despite all the advances seen in recent years, the severe adverse effects and low specificity
of conventional chemotherapy are still challenging problems regarding cancer treatment …
of conventional chemotherapy are still challenging problems regarding cancer treatment …
Progress in natural compounds/siRNA co-delivery employing nanovehicles for cancer therapy
M Ashrafizadeh, A Zarrabi, K Hushmandi… - ACS combinatorial …, 2020 - ACS Publications
Chemotherapy using natural compounds, such as resveratrol, curcumin, paclitaxel,
docetaxel, etoposide, doxorubicin, and camptothecin, is of importance in cancer therapy …
docetaxel, etoposide, doxorubicin, and camptothecin, is of importance in cancer therapy …
Nanogels as novel nanocarrier systems for efficient delivery of CNS therapeutics
Y Zhang, Z Zou, S Liu, S Miao, H Liu - Frontiers in Bioengineering and …, 2022 - frontiersin.org
Nanogels have come out as a great potential drug delivery platform due to its prominently
high colloidal stability, high drug loading, core-shell structure, good permeation property and …
high colloidal stability, high drug loading, core-shell structure, good permeation property and …
Chitosan surface-modified PLGA nanoparticles loaded with cranberry powder extract as a potential oral delivery platform for targeting colon cancer cells
Nutraceutical cranberry powder extract (CBPE) has distinct polyphenols inhibiting colon
cancer growth and proliferation. However, its oral therapeutic efficacy is hindered because …
cancer growth and proliferation. However, its oral therapeutic efficacy is hindered because …
Evaluation of cell proliferation and wound healing effects of vitamin A palmitate-loaded PLGA/chitosan-coated PLGA nanoparticles: Preparation, characterization …
L Baghirova, E Kaya Tilki, AA Ozturk - ACS omega, 2023 - ACS Publications
In this study, vitamin A palmitate (VAP)-loaded poly (lactic-co-glycolic acid)(PLGA)/chitosan-
coated PLGA nanoparticle (NP) systems were prepared by the nanoprecipitation technique …
coated PLGA nanoparticle (NP) systems were prepared by the nanoprecipitation technique …
Novel formulations and drug delivery systems to administer biological solids
Recent advances in formulation sciences have expanded the previously limited design
space for biological modalities, including peptide, protein, and vaccine products. At the …
space for biological modalities, including peptide, protein, and vaccine products. At the …