RNAi-based therapeutics and tumor targeted delivery in cancer

G Kara, GA Calin, B Ozpolat - Advanced drug delivery reviews, 2022 - Elsevier
Over the past decade, non-coding RNA-based therapeutics have proven as a great potential
for the development of targeted therapies for cancer and other diseases. The discovery of …

Solid lipid nanoparticles and nanostructured lipid carriers: A review emphasizing on particle structure and drug release

A Gordillo-Galeano, CE Mora-Huertas - European Journal of Pharmaceutics …, 2018 - Elsevier
Colloidal systems based on lipids have attracted attention during the last two decades as a
delivery method of drugs that are poorly soluble in water. The investigations carried out have …

Pectin co-functionalized dual layered solid lipid nanoparticle made by soluble curcumin for the targeted potential treatment of colorectal cancer

JM Mohamed, A Alqahtani, F Ahmad… - Carbohydrate …, 2021 - Elsevier
Highlights•Dual layered solid lipid nanoparticle (DL-SLN) containing the soluble curcumin
(SC) complex investigated for the first time.•Molecular docking and interaction study of DL …

Co-delivery of curcumin and Bcl-2 siRNA by PAMAM dendrimers for enhancement of the therapeutic efficacy in HeLa cancer cells

M Ghaffari, G Dehghan, B Baradaran… - Colloids and Surfaces B …, 2020 - Elsevier
Co-delivery of therapeutic agents and small interfering RNA (siRNA) can be achieved by a
suitable nanovehicle. In this work, the solubility and bioavailability of curcumin (Cur) were …

[HTML][HTML] Solid lipid nanoparticles: multitasking nano-carriers for cancer treatment

J German-Cortés, M Vilar-Hernández, D Rafael… - Pharmaceutics, 2023 - mdpi.com
Despite all the advances seen in recent years, the severe adverse effects and low specificity
of conventional chemotherapy are still challenging problems regarding cancer treatment …

Progress in natural compounds/siRNA co-delivery employing nanovehicles for cancer therapy

M Ashrafizadeh, A Zarrabi, K Hushmandi… - ACS combinatorial …, 2020 - ACS Publications
Chemotherapy using natural compounds, such as resveratrol, curcumin, paclitaxel,
docetaxel, etoposide, doxorubicin, and camptothecin, is of importance in cancer therapy …

Nanogels as novel nanocarrier systems for efficient delivery of CNS therapeutics

Y Zhang, Z Zou, S Liu, S Miao, H Liu - Frontiers in Bioengineering and …, 2022 - frontiersin.org
Nanogels have come out as a great potential drug delivery platform due to its prominently
high colloidal stability, high drug loading, core-shell structure, good permeation property and …

Chitosan surface-modified PLGA nanoparticles loaded with cranberry powder extract as a potential oral delivery platform for targeting colon cancer cells

MM Mostafa, MM Amin, MY Zakaria, MA Hussein… - Pharmaceutics, 2023 - mdpi.com
Nutraceutical cranberry powder extract (CBPE) has distinct polyphenols inhibiting colon
cancer growth and proliferation. However, its oral therapeutic efficacy is hindered because …

Evaluation of cell proliferation and wound healing effects of vitamin A palmitate-loaded PLGA/chitosan-coated PLGA nanoparticles: Preparation, characterization …

L Baghirova, E Kaya Tilki, AA Ozturk - ACS omega, 2023 - ACS Publications
In this study, vitamin A palmitate (VAP)-loaded poly (lactic-co-glycolic acid)(PLGA)/chitosan-
coated PLGA nanoparticle (NP) systems were prepared by the nanoprecipitation technique …

Novel formulations and drug delivery systems to administer biological solids

Y Zhang, DA Davis, K AboulFotouh, J Wang… - Advanced drug delivery …, 2021 - Elsevier
Recent advances in formulation sciences have expanded the previously limited design
space for biological modalities, including peptide, protein, and vaccine products. At the …