The role of Th17 cells in viral infections

PS Aghbash, N Hemmat, JS Nahand… - International …, 2021 - Elsevier
The present review provides an overview of recent advances regarding the function of Th17
cells and their produced cytokines in the progression of viral diseases. Viral infections alone …

[HTML][HTML] Robust T cell response toward spike, membrane, and nucleocapsid SARS-CoV-2 proteins is not associated with recovery in critical COVID-19 patients

CJ Thieme, M Anft, K Paniskaki… - Cell Reports …, 2020 - cell.com
T cell immunity toward SARS-CoV-2 spike (S-), membrane (M-), and nucleocapsid (N-)
proteins may define COVID-19 severity. Therefore, we compare the SARS-CoV-2-reactive T …

[HTML][HTML] BK polyomavirus: latency, reactivation, diseases and tumorigenesis

X Zhou, C Zhu, H Li - Frontiers in Cellular and Infection Microbiology, 2023 - frontiersin.org
The identification of the first human polyomavirus BK (BKV) has been over half century, The
previous epidemiological and phylogenetic studies suggest that BKV prevailed and co …

[HTML][HTML] Reactivation of multiple viruses in patients with sepsis

AH Walton, JT Muenzer, D Rasche, JS Boomer, B Sato… - PloS one, 2014 - journals.plos.org
A current controversy is whether patients with sepsis progress to an immunosuppressed
state. We hypothesized that reactivation of latent viruses occurred with prolonged sepsis …

The quality of SARS-CoV-2–specific T cell functions differs in patients with mild/moderate versus severe disease, and T cells expressing coinhibitory receptors are …

S Shahbaz, L Xu, W Sligl, M Osman… - The Journal of …, 2021 - journals.aai.org
Understanding the function of SARS-CoV-2 Ag-specific T cells is crucial for the monitoring of
antiviral immunity and vaccine design. Currently, both impaired and robust T cell immunity is …

[HTML][HTML] TCR repertoire analysis by next generation sequencing allows complex differential diagnosis of T cell–related pathology

M Dziubianau, J Hecht, L Kuchenbecker… - American journal of …, 2013 - Elsevier
Clonotype analysis is essential for complete characterization of antigen-specific T cells.
Moreover, knowledge on clonal identity allows tracking of antigen-specific T cells in whole …

[HTML][HTML] BKV, CMV, and EBV interactions and their effect on graft function one year post-renal transplantation: results from a large multi-centre study

A Blazquez-Navarro, C Dang-Heine, N Wittenbrink… - …, 2018 - thelancet.com
Abstract Background BK virus (BKV), Cytomegalovirus (CMV) and Epstein-Barr virus (EBV)
reactivations are common after kidney transplantation and associated with increased …

[HTML][HTML] Virus-associated nephropathies: a narrative review

C Masset, P Le Turnier, C Bressollette-Bodin… - International Journal of …, 2022 - mdpi.com
While most viral infections cause mild symptoms and a spontaneous favorable resolution,
some can lead to severe or protracted manifestations, specifically in immunocompromised …

Management of polyomavirus-associated nephropathy in renal transplant recipients

DRJ Kuypers - Nature Reviews Nephrology, 2012 - nature.com
Polyomavirus-associated nephropathy (PVAN) remains an important infectious complication
after renal transplantation, affecting 1–10% of recipients and causing graft loss in …

[HTML][HTML] COVID-19-induced ARDS is associated with decreased frequency of activated memory/effector T cells expressing CD11a++

M Anft, K Paniskaki, A Blazquez-Navarro, A Doevelaar… - Molecular Therapy, 2020 - cell.com
Preventing the progression to acute respiratory distress syndrome (ARDS) in COVID-19 is
an unsolved challenge. The involvement of T cell immunity in this exacerbation remains …