Molecular models of bidirectional promoter regulation

S Nemsick, AS Hansen - Current Opinion in Structural Biology, 2024 - Elsevier
Approximately 11% of human genes are transcribed by a bidirectional promoter (BDP),
defined as two genes with< 1 kb between their transcription start sites. Despite their …

Structural basis of a transcription pre-initiation complex on a divergent promoter

JJG Colón, L Palao, SF Chen, HJ Kim, L Snyder… - Molecular cell, 2023 - cell.com
Most eukaryotic promoter regions are divergently transcribed. As the RNA polymerase II pre-
initiation complex (PIC) is intrinsically asymmetric and responsible for transcription in a …

[HTML][HTML] SWI/SNF-dependent genes are defined by their chromatin landscape

L Basurto-Cayuela, JA Guerrero-Martínez… - Cell Reports, 2024 - cell.com
SWI/SNF complexes are evolutionarily conserved, ATP-dependent chromatin remodeling
machines. Here, we characterize the features of SWI/SNF-dependent genes using BRM014 …

[PDF][PDF] Structural Biology

S Nemsick, AS Hansen - Current Opinion in Structural Biology, 2024 - ashansenlab.com
Approximately 11% of human genes are transcribed by a bidirectional promoter (BDP),
defined as two genes with< 1 kb between their transcription start sites. Despite their …

Size fractionated NET‐Seq reveals a conserved architecture of transcription units around yeast genes

S Xi, T Nguyen, S Murray, P Lorenz, J Mellor - Yeast, 2024 - Wiley Online Library
Genomes from yeast to humans are subject to pervasive transcription. A single round of
pervasive transcription is sufficient to alter local chromatin conformation, nucleosome …

Inhibición de la actividad ATPasa del complejo SWI/SNF: cambios cromatínicos y de la expresión génica

L Basurto Cayuela - 2023 - digital.csic.es
Los complejos SWI/SNF fueron la primera maquinaria de remodelación de cromatina
dependiente de ATP descubierta y están compuestos por 11-15 proteínas diferentes en …