Post-hepatectomy liver failure: A timeline centered review

M Bekheit, L Grundy, AKA Salih, P Bucur… - … & Pancreatic Diseases …, 2023 - Elsevier
Background Post-hepatectomy liver failure (PHLF) is a leading cause of postoperative
mortality after liver surgery. Due to its significant impact, it is imperative to understand the …

[HTML][HTML] Surgical Implications for Nonalcoholic Steatohepatitis-Related Hepatocellular Carcinoma

CR Anbarasu, S Williams-Perez, ER Camp, DJ Erstad - Cancers, 2024 - mdpi.com
Simple Summary Hepatocellular carcinoma (HCC) is an aggressive form of liver cancer that
arises in a background of chronic hepatic injury. Metabolic syndrome-associated fatty liver …

Liver growth prediction in ALPPS–A multicenter analysis from the international ALPPS registry

V Lopez‐Lopez, M Linecker, J Cruz… - Liver …, 2022 - Wiley Online Library
Background While ALPPS triggers a fast liver hypertrophy, it is still unclear which factors
matter most to achieve accelerated hypertrophy within a short period of time. The aim of the …

Influence of diabetes on short-term outcome after major hepatectomy: an underestimated risk?

A Fischer, J Fuchs, C Stravodimos, U Hinz, A Billeter… - BMC surgery, 2020 - Springer
Background Patient-related risk factors such as diabetes mellitus and obesity are increasing
in western countries. At the same time the indications for liver resection in both benign and …

Impact of laparoscopic liver resection on liver regeneration

Y Matsuo, D Hokuto, S Yasuda, T Yoshikawa… - Surgical …, 2022 - Springer
Background Liver regeneration after liver resection plays an important role in preventing
posthepatectomy liver failure. In this study, we aimed to evaluate and compare the impact of …

Short-and long-term impacts of overweight status on outcomes among living liver donors

W Fang, K Gotoh, S Kobayashi, K Sasaki… - Transplantation …, 2022 - Elsevier
Purpose In recent years, the increasing number of obese individuals in Japan has made
transplant teams sometimes forced to select candidates with a high body mass index (BMI) …

Model-based virtual patient analysis of human liver regeneration predicts critical perioperative factors controlling the dynamic mode of response to resection

BK Verma, P Subramaniam, R Vadigepalli - BMC Systems Biology, 2019 - Springer
Background Liver has the unique ability to regenerate following injury, with a wide range of
variability of the regenerative response across individuals. Existing computational models of …

Hepatic epigenetic reprogramming after liver resection in offspring alleviates the effects of maternal obesity

LAP Simino, MF Fontana, T de Fante… - Frontiers in Cell and …, 2022 - frontiersin.org
Obesity has become a public health problem in recent decades, and during pregnancy, it
can lead to an increased risk of gestational complications and permanent changes in the …

Maternal high-fat diet consumption programs male offspring to mitigate complications in liver regeneration

T Fante, LAP Simino, MF Fontana… - … origins of health and …, 2022 - cambridge.org
In the last decades, obesity and nonalcoholic fatty liver disease (NAFLD) have become
increasingly prevalent in wide world. Fatty liver can be detrimental to liver regeneration (LR) …

[HTML][HTML] Diabetes mellitus and postoperative blood glucose value help predict posthepatectomy liver failure in patients with hepatocellular carcinoma

J Luo, L Xu, L Li, J Zhang, M Zhang… - Journal of Gastrointestinal …, 2021 - ncbi.nlm.nih.gov
Background Many complications after hepatectomy can lead to perioperative death, among
which posthepatectomy liver failure (PHLF) is the leading one. Existing studies suggest that …