An investigation into the effects of geometric scaling and pore structure on drug dose and release of 3D printed solid dosage forms

T McDonagh, P Belton, S Qi - European Journal of Pharmaceutics and …, 2022 - Elsevier
A range of 3D printing methods have been investigated intensively in the literature for
manufacturing personalised solid dosage forms, with infill density commonly used to control …

New insights into the effects of porosity, pore length, pore shape and pore alignment on drug release from extrusionbased additive manufactured pharmaceuticals

B Zhang, A Gleadall, P Belton, T Mcdonagh, R Bibb… - Additive …, 2021 - Elsevier
Material extrusionbased additive manufacturing (ME-AM) has been recently adopted by the
pharmaceutical field as a potential method for decentralised small-batch manufacturing of …

A simple and inexpensive image analysis technique to study the effect of disintegrants concentration and diluents type on disintegration

A Berardi, L Bisharat, A Blaibleh, L Pavoni… - Journal of …, 2018 - Elsevier
Tablets disintegration is often the result of a size expansion of the tablets. In this study, we
quantified the extent and direction of size expansion of tablets during disintegration, using …

Disintegration testing augmented by computer Vision technology

S Floryanzia, P Ramesh, M Mills, S Kulkarni… - International Journal of …, 2022 - Elsevier
Oral solid dosage forms, specifically immediate release tablets, are prevalent in the
pharmaceutical industry. Disintegration testing is often the first step of commercialization and …

Direct granule feeding of thermal droplet deposition 3D printing of porous pharmaceutical solid dosage forms free of plasticisers

T McDonagh, P Belton, S Qi - Pharmaceutical Research, 2022 - Springer
Purpose To develop a new direct granule fed 3D printing method for manufacturing
pharmaceutical solid dosage forms with porous structures using a thermal droplet deposition …

Hot-melt extrusion process impact on polymer choice of glyburide solid dispersions: The effect of wettability and dissolution

M Alshafiee, MK Aljammal, D Markl, A Ward… - International Journal of …, 2019 - Elsevier
The aim of this study was to evaluate the choice of polymer and polymer level on the
performance of the microstructure and wettability of hot-melt extruded solid dispersion of …

The influence of ethanol on superdisintegrants and on tablets disintegration

L Bisharat, HS AlKhatib, S Muhaissen… - European Journal of …, 2019 - Elsevier
Disintegration of immediate release tablets originates from the volume expansion of
disintegrants within the formulation. Here, we study the impact of ethanol on the disintegrant …

The use of visible and UV dissolution imaging for the assessment of propranolol hydrochloride in liquisolid compacts of Sesamum radiatum gum

A Ward, K Walton, S Stoycheva, M Wallis… - Journal of Drug Delivery …, 2020 - Elsevier
This work explores the first use of UV imaging in liquisolid systems. The aim of this study
was to simultaneously measure a model drug propranolol hydrochloride (PPN) release and …

[HTML][HTML] Rapid releasing naproxen Liqui-Pellet using effervescent agent and neusilin US2

M Lam, K Asare-Addo, A Nokhodchi - Iranian Journal of Basic …, 2021 - ncbi.nlm.nih.gov
Objective (s): Liqui-Mass technology has shown promising advantages in terms of
commercial production and formulation manipulation. This study attempts to further explore …

Synthesis of polyacrylonitrile nanoflowers and their controlled pH-sensitive drug release behavior

Q Lian, H Liu, X Zheng, D Jia, C Liu, D Wang - RSC advances, 2020 - pubs.rsc.org
A novel controlled drug release system based on pH sensitive polyacrylonitrile (PAN)
nanoflowers in different kinds of solvents was successfully prepared with …