[HTML][HTML] Tumor-induced inflammatory cytokines and the emerging diagnostic devices for cancer detection and prognosis

AER Kartikasari, CS Huertas, A Mitchell… - Frontiers in …, 2021 - frontiersin.org
Chronic inflammation generated by the tumor microenvironment is known to drive cancer
initiation, proliferation, progression, metastasis, and therapeutic resistance. The tumor …

Potential therapeutic effects of curcumin mediated by JAK/STAT signaling pathway: a review

M Ashrafizadeh, H Rafiei… - Phytotherapy …, 2020 - Wiley Online Library
Curcumin is a naturally occurring nutraceutical compound with a number of therapeutic and
biological activities such as antioxidant, anti‐inflammatory, anti‐diabetic, antitumor, and …

[HTML][HTML] JAK-STAT signalling pathway in cancer

AJ Brooks, T Putoczki - Cancers, 2020 - mdpi.com
JAK-STAT signalling is a cornerstone to cancer progression, either as a tumour intrinsic
driver of cancer growth/metastasis, or as a modulator of immune surveillance. This Special …

[HTML][HTML] Electrochemical biosensors for cytokine profiling: recent advancements and possibilities in the near future

N Dutta, PB Lillehoj, P Estrela, G Dutta - Biosensors, 2021 - mdpi.com
Cytokines are soluble proteins secreted by immune cells that act as molecular messengers
relaying instructions and mediating various functions performed by the cellular counterparts …

Tangeretin: A mechanistic review of its pharmacological and therapeutic effects

M Ashrafizadeh, Z Ahmadi… - Journal of basic and …, 2020 - degruyter.com
To date, a large number of synthetic drugs have been developed for the treatment and
prevention of different disorders, such as neurodegenerative diseases, diabetes mellitus …

[HTML][HTML] Phosphoflow cytometry to assess cytokine signaling pathways in peripheral immune cells: potential for inferring immune cell function and treatment response …

NJ Toney, J Schlom, RN Donahue - Journal of Experimental & Clinical …, 2023 - Springer
Tumor biopsy is often not available or difficult to obtain in patients with solid tumors.
Investigation of the peripheral immune system allows for in-depth and dynamic profiling of …

[HTML][HTML] Cytokine and cancer biomarkers detection: the dawn of electrochemical paper-based biosensor

SW Loo, TS Pui - Sensors, 2020 - mdpi.com
Although the established ELISA-based sensing platforms have many benefits, the
importance of cytokine and cancer biomarkers detection for point-of-care diagnostics has …

[HTML][HTML] Liquid biopsy in pre-metastatic niche: from molecular mechanism to clinical application

Z Liu, Y Kong, Q Dang, S Weng, Y Zheng… - Frontiers in …, 2022 - frontiersin.org
Metastatic dissemination represents a hallmark of cancer that is responsible for the high
mortality rate. Recently, emerging evidence demonstrates a time-series event—pre …

[HTML][HTML] Influence of long non-coding RNA in the regulation of cancer stem cell signaling pathways

K Sonawala, S Ramalingam, I Sellamuthu - Cells, 2022 - mdpi.com
Over the past two decades, cancer stem cells (CSCs) have emerged as an immensely
studied and experimental topic, however a wide range of questions concerning the topic still …

[HTML][HTML] Optimized screening of DNA methylation sites combined with gene expression analysis to identify diagnostic markers of colorectal cancer

Z Ye, G Song, J Liang, S Yi, Y Gao, H Jiang - BMC cancer, 2023 - Springer
Background The prognosis of patients with colorectal cancer is related to early detection.
However, commonly used screening markers lack sensitivity and specificity. In this study, we …