Extracellular vesicles (EVs) are very attractive as carriers of active components due to their
good immunological and their ability to penetrate the physiological barrier that synthetic …

β2 integrins are transmembrane receptors that exist widely in human immune cells and
participate in pathological processes such as chronic inflammation, thrombosis, and …

Background Antcin K, an extract of Antrodia cinnamomea (a medicinal mushroom endemic
to Taiwan commonly used in Chinese medicine preparations), inhibits proinflammatory …

Bone loss is a major issue for patients with osteoporosis, arthritis, periodontitis, and bone
metastasis; however, anti-resorption drugs used to treat bone loss have been linked to a …

Chondrosarcoma is a primary malignant bone tumor. Traditional therapy is not very effective,
and it is prone to metastasis in the late stage. The tumor microenvironment (TME) plays a …

Abstract Ohwia caudata (Thunb.) H. Ohashi (Leguminosae) also called as “Evergreen
shrub” and Artemisia argyi H. Lév. and Vaniot (Compositae) also named as “Chinese …

Lung cancer is an extremely common cancer and metastatic lung cancer has a greatly low
survival rate. Lymphangiogenesis is essential for the development and metastasis of lung …

Osteosarcoma is a highly mortal bone tumor, with a high metastatic potential, promoted in
part by the enzyme procollagen-lysine 2-oxoglutarate 5-dioxygenase 2 (PLOD2). Increasing …

Osteoarthritis (OA) is characterized by the infiltration and adhesion of monocytes into the
inflamed joint synovium. Interleukin (IL)-17 is a critical inflammatory mediator that …

New treatments for chondrosarcoma are extremely important. Chondrosarcoma is a primary
malignant bone tumor with a very unfavorable prognosis. High-grade chondrosarcoma has …