Liver cirrhosis, the end-stage of every chronic liver disease, is not only the major risk factor
for the development of hepatocellular carcinoma but also a limiting factor for anticancer …

The difficult problem faced by multiple generation of practicing physicians is determining the
cause of abnormal liver function tests in cancer patients on chemotherapy. Hepatotoxicity …

The Tenth Edition of the Handbook of Clinical Drug Data continues a long tradition of
providing clinically relevant, well-referenced drug information compiled by expert clinicians …

Featuring more than 4100 references, Drug-Induced Liver Disease is an invaluable
reference for gastroenterologists, hepatologists, family physicians, internists, pathologists …

Triggered drug delivery strategies have been shown to enhance drug accumulation at target
diseased sites in comparison to administration of free drug. In particular, many studies have …

The elderly comprise the majority of patients with cancer and are the recipients of the
greatest amount of chemotherapy. Unfortunately, there is a lack of data to make evidence …

Modifications to bodily functions and physiology are known to occur with age. These
changes can have a considerable impact on the pharmacokinetic processes of absorption …

This report reviews published information on the clinical pharmacokinetics of antitumour
agents in patients with liver dysfunction, associated with primary liver disease or liver …

The liver is fundamentally important in drug metabolism. In oncology, the astute clinician
must not only understand the meaning and limitations of commonly ordered liver …

Major advances in carrier-mediated agents, which include nanoparticles, nanosomes and
conjugates, have revolutionized drug delivery capabilities over the past decade. While …