Formulation of poloxamers for drug delivery

AM Bodratti, P Alexandridis - Journal of functional biomaterials, 2018 - mdpi.com
Poloxamers, also known as Pluronics®, are block copolymers of poly (ethylene oxide)(PEO)
and poly (propylene oxide)(PPO), which have an amphiphilic character and useful …

Poloxamer: A versatile tri-block copolymer for biomedical applications

P Zarrintaj, JD Ramsey, A Samadi, Z Atoufi, MK Yazdi… - Acta biomaterialia, 2020 - Elsevier
Poloxamers, also called Pluronic, belong to a unique class of synthetic tri-block copolymers
containing central hydrophobic chains of poly (propylene oxide) sandwiched between two …

Encapsulation of hydrophobic drugs in Pluronic F127 micelles: effects of drug hydrophobicity, solution temperature, and pH

R Basak, R Bandyopadhyay - Langmuir, 2013 - ACS Publications
Three drugs, ibuprofen, aspirin, and erythromycin, are encapsulated in spherical Pluronic
F127 micelles. The shapes and the size distributions of the micelles in dilute, aqueous …

Direct and reverse pluronic micelles: Design and characterization of promising drug delivery nanosystems

A Naharros-Molinero, MÁ Caballo-González… - Pharmaceutics, 2022 - mdpi.com
Pluronics are a family of amphiphilic block copolymers broadly explored in the
pharmaceutical field. Under certain conditions, Pluronics self-assemble in different …

Pluronic-based nanovehicles: Recent advances in anticancer therapeutic applications

I Jarak, CL Varela, ET da Silva, FFM Roleira… - European Journal of …, 2020 - Elsevier
Pluronics are a class of amphiphilic tri-block copolymers with wide pharmaceutical
applicability. In the past decades, the ability to form biocompatible nanosized micelles was …

Aliphatic polyethers: classical polymers for the 21st century

R Klein, FR Wurm - Macromolecular rapid communications, 2015 - Wiley Online Library
Polyethers—polymers with the structural element (R'‐O‐R) n in their backbone—are an old
class of polymers which were already used at the time of the ancient Egyptians. However …

Role of non-covalent and covalent interactions in cargo loading capacity and stability of polymeric micelles

X Ke, VWL Ng, RJ Ono, JMW Chan… - Journal of Controlled …, 2014 - Elsevier
Polymeric micelles self-assembled from biodegradable amphiphilic block copolymers have
been proven to be effective drug delivery carriers that reduce the toxicity and enhance the …

Improved solubility, dissolution, and oral bioavailability for atorvastatin-Pluronic® solid dispersions

MA Shaker, HM Elbadawy, MA Shaker - International Journal of …, 2020 - Elsevier
Despite the status of atorvastatin (AT) as one of the top selling statins for prophylaxis against
primary and secondary cardiovascular diseases, its limited oral absorption limits its full …

Comprehensive review of Pluronic® polymers of different shapes with prominent applications in photodynamic therapy

SS Kumar, KK Harikrishnan, SP Urmila, V Gauri… - European Polymer …, 2023 - Elsevier
In this review, we have highlighted different types of Pluronic® polymers for prominent
photodynamic therapy (PDT) applications. To begin with, we have provided the definition …

Pluronic-SAILs (surface active ionic liquids) mixed micelles as efficient hydrophobic quercetin drug carriers

P Singla, O Singh, S Chabba, RK Mahajan - Journal of Molecular Liquids, 2018 - Elsevier
The present manuscript reports a systematic investigation on the solubilization of
hydrophobic drug Quercetin (QCT) in pluronic F108 and its mixed micelles with surface …