It is known that the chemokine receptor CXCR7 (RDC1) can be engaged by both
chemokines CXCL12 (SDF-1) and CXCL11 (I-TAC), but the exact expression pattern and …

Stromal cell-derived factor-1 is a chemoattractant produced by bone marrow stromal cell
lines. It is recognized as a critical factor in the immune and central nervous systems (CNSs) …

Chemokines are chemoattractants that can regulate cell movement and adhesion. SDF-1
[stromal cell-derived factor-1 (SDF-1)] is a homeostatic CXC chemokine. SDF-1 and its …

Recruitment of inflammatory cells is known to drive the secondary damage cascades that
are common to injuries of the central nervous system (CNS). Cell activation and infiltration to …

We review the pivotal role of the stromal derived factor (SDF)-1 chemokine in tissue
ischaemia and how it orchestrates the rapid revascularization of injured, ischaemic, and …

Systemic administration of MSCs resulted in remarkable functional improvements in injured
tissues without either long‐term engraftment or differentiation in many clinical and …

Pial collaterals provide protection in stroke. Evidence suggests their formation late during
gestation (collaterogenesis) is driven by reduced oxygen levels in the cerebral watersheds …

CXC chemokine receptor 7 (CXCR7) is a G-protein-coupled receptor that signals through
the β-arrestin pathway. Its ligands include interferon-inducible T cell α chemoattractant …

Chemokine CXCL12 is widely expressed in the central nervous system and essential for the
proper functioning of human neural progenitor cells (hNPCs). Although CXCL12 is known to …

Abstract The chemokine SDF-1/CXCL12 induces and modulates major steps of
ontogenesis, regeneration and tumorigenesis. Depending on the organ or tissue, CXCL12 …