Accurate DNA repair and replication are critical for genomic stability and cancer prevention.
RAD51 and its gene family are key regulators of DNA fidelity through diverse roles in double …

Homology-dependent exchange of genetic information between DNA molecules has a
profound impact on the maintenance of genome integrity by facilitating error-free DNA …

Homologous recombination (HR) is critical both for repairing DNA lesions in mitosis and for
chromosomal pairing and exchange during meiosis. However, some forms of HR can also …

The Rad51 paralogs are required for homologous recombination (HR) and the maintenance
of genomic stability. The molecular mechanisms by which the five vertebrate Rad51 …

In this review we focus on new insights that challenge our understanding of homologous
recombination (HR) and Rad51 regulation. Recent advances using high-resolution …

Homologous recombination (HR) contributes to maintaining genome integrity by facilitating
error-free repair of DNA double-strand breaks (DSBs) primarily during the S and G2 phases …

DNA-damage tolerance (DDT) is employed by eukaryotic cells to bypass replication-
blocking lesions induced by DNA-damaging agents. In budding yeast Saccharomyces …

The conserved budding yeast Rad51 paralogues, including Rad55, Rad57, Csm2 and Psy3
are indispensable for homologous recombination (HR)-mediated chromosome damage …

During homologous recombination, eukaryotic RecA homologue Rad51 assembles into a
nucleoprotein filament on single-stranded DNA to catalyse homologous pairing and DNA …

The repair of DNA by homologous recombination is an essential, efficient, and high-fidelity
process that mends DNA lesions formed during cellular metabolism; these lesions include …