Physiology of astroglia
A Verkhratsky, M Nedergaard - Physiological reviews, 2018 - journals.physiology.org
Astrocytes are neural cells of ectodermal, neuroepithelial origin that provide for homeostasis
and defense of the central nervous system (CNS). Astrocytes are highly heterogeneous in …
and defense of the central nervous system (CNS). Astrocytes are highly heterogeneous in …
[HTML][HTML] Involvement of astrocytes in Alzheimer's disease from a neuroinflammatory and oxidative stress perspective
RE González-Reyes, MO Nava-Mesa… - Frontiers in molecular …, 2017 - frontiersin.org
Alzheimer disease (AD) is a frequent and devastating neurodegenerative disease in
humans, but still no curative treatment has been developed. Although many explicative …
humans, but still no curative treatment has been developed. Although many explicative …
Astrocyte calcium signaling: the third wave
N Bazargani, D Attwell - Nature neuroscience, 2016 - nature.com
The discovery that transient elevations of calcium concentration occur in astrocytes, and
release'gliotransmitters' which act on neurons and vascular smooth muscle, led to the idea …
release'gliotransmitters' which act on neurons and vascular smooth muscle, led to the idea …
Astrocytes in physiological aging and Alzheimer's disease
Astrocytes are fundamental for homoeostasis, defence and regeneration of the central
nervous system. Loss of astroglial function and astroglial reactivity contributes to the aging of …
nervous system. Loss of astroglial function and astroglial reactivity contributes to the aging of …
[HTML][HTML] Astrocytes as guardians of neuronal excitability: mechanisms underlying epileptogenesis
QP Verhoog, L Holtman, E Aronica… - Frontiers in …, 2020 - frontiersin.org
Astrocytes are key homeostatic regulators in the central nervous system and play important
roles in physiology. After brain damage caused by eg, status epilepticus, traumatic brain …
roles in physiology. After brain damage caused by eg, status epilepticus, traumatic brain …
Glial cells in Alzheimer's disease: From neuropathological changes to therapeutic implications
MS Uddin, LW Lim - Ageing research reviews, 2022 - Elsevier
Alzheimer's disease (AD) is a neurodegenerative disorder that usually develops slowly and
progressively worsens over time. Although there has been increasing research interest in …
progressively worsens over time. Although there has been increasing research interest in …
[HTML][HTML] Astrocytes as a therapeutic target in alzheimer's disease–comprehensive review and recent developments
M Rodríguez-Giraldo, RE González-Reyes… - International Journal of …, 2022 - mdpi.com
Alzheimer's disease (AD) is a frequent and disabling neurodegenerative disorder, in which
astrocytes participate in several pathophysiological processes including neuroinflammation …
astrocytes participate in several pathophysiological processes including neuroinflammation …
Glial cells in (patho) physiology
J. Neurochem.(2012) 121, 4–27. Abstract Neuroglial cells define brain homeostasis and
mount defense against pathological insults. Astroglia regulate neurogenesis and …
mount defense against pathological insults. Astroglia regulate neurogenesis and …
[HTML][HTML] Astrocytes regulate brain extracellular pH via a neuronal activity-dependent bicarbonate shuttle
Brain cells continuously produce and release protons into the extracellular space, with the
rate of acid production corresponding to the levels of neuronal activity and metabolism …
rate of acid production corresponding to the levels of neuronal activity and metabolism …
Local Ca2+ detection and modulation of synaptic release by astrocytes
Astrocytes communicate with synapses by means of intracellular calcium ([Ca2+] i)
elevations, but local calcium dynamics in astrocytic processes have never been thoroughly …
elevations, but local calcium dynamics in astrocytic processes have never been thoroughly …