The chemistry and biochemistry of vanadium and the biological activities exerted by vanadium compounds

DC Crans, JJ Smee, E Gaidamauskas… - Chemical reviews, 2004 - ACS Publications
Vanadium is a trace element, which may be beneficial and possibly essential in humans1
but certainly essential for some living organisms. 2r11 Metal ions and thus vanadium ions …

The catalytic mechanisms of binuclear metallohydrolases

N Mitić, SJ Smith, A Neves, LW Guddat… - Chemical …, 2006 - ACS Publications
Binuclear metallohydrolases are a structurally diverse group of enzymes that use binuclear
metal ion centers to catalyze the hydrolysis of amides and esters of carboxylic and …

Phosphorylation-mediated RNA/peptide complex coacervation as a model for intracellular liquid organelles

WM Aumiller Jr, CD Keating - Nature chemistry, 2016 - nature.com
Biological cells are highly organized, with numerous subcellular compartments.
Phosphorylation has been hypothesized as a means to control the assembly/disassembly of …

Non-equilibrium steady states in supramolecular polymerization

A Sorrenti, J Leira-Iglesias, A Sato… - Nature …, 2017 - nature.com
Living systems use fuel-driven supramolecular polymers such as actin to control important
cell functions. Fuel molecules like ATP are used to control when and where such polymers …

Vanadium–phosphatase complexes: Phosphatase inhibitors favor the trigonal bipyramidal transition state geometries

CC McLauchlan, BJ Peters, GR Willsky… - Coordination Chemistry …, 2015 - Elsevier
Over the past two decades increasing information about the function and structural detail of
phosphatases has become available detailing the interaction with vanadate or other …

Phosphorylation of the cytokinesis regulator ECT2 at G2/M phase stimulates association of the mitotic kinase Plk1 and accumulation of GTP-bound RhoA

F Niiya, T Tatsumoto, KS Lee, T Miki - Oncogene, 2006 - nature.com
The epithelial cell transforming gene 2 (ECT2) protooncogene encodes a Rho exchange
factor, and regulates cytokinesis. ECT2 is phosphorylated in G2/M phases, but its role in the …

Metal binding studies and EPR spectroscopy of the manganese transport regulator MntR

MV Golynskiy, WA Gunderson, MP Hendrich… - Biochemistry, 2006 - ACS Publications
Manganese transport regulator (MntR) is a member of the diphtheria toxin repressor (DtxR)
family of transcription factors that is responsible for manganese homeostasis in Bacillus …

The yeast Mig1 transcriptional repressor is dephosphorylated by glucose-dependent and-independent mechanisms

S Shashkova, AJM Wollman, MC Leake… - FEMS microbiology …, 2017 - academic.oup.com
A yeast Saccharomyces cerevisiae Snf1 kinase, an analog of mammalian AMPK, regulates
glucose derepression of genes required for utilization of alternative carbon sources through …

Bistability of a coupled Aurora B kinase-phosphatase system in cell division

AV Zaytsev, D Segura-Pena, M Godzi, A Calderon… - elife, 2016 - elifesciences.org
Aurora B kinase, a key regulator of cell division, localizes to specific cellular locations, but
the regulatory mechanisms responsible for phosphorylation of substrates located remotely …

The Rv0805 Gene from Mycobacterium tuberculosis Encodes a 3',5'-Cyclic Nucleotide Phosphodiesterase:  Biochemical and Mutational Analysis

AR Shenoy, N Sreenath, M Podobnik, M Kovacevic… - Biochemistry, 2005 - ACS Publications
Mycobacterium tuberculosis is an important human pathogen and has developed
sophisticated mechanisms to evade the host immune system. These could involve the use of …