Infections are one of the major selective pressures acting on humans, and host-pathogen
interactions contribute to shaping the genetic diversity of both organisms. Evolutionary …

The nematode Caenorhabditis elegans is now a major model organism in biology. The
choice of Sydney Brenner to adopt this species in the mid-1960s and the success of his …

Microbes can defend their host against virulent infections, but direct evidence for the
adaptive origin of microbe-mediated protection is lacking. Using experimental evolution of a …

Although many studies have examined quantitative trait variation across many species, only
a small number of genes and thereby molecular mechanisms have been discovered …

Recently interest in multi-generational epigenetic phenomena have been fuelled by highly
reproducible intergenerational and transgenerational inheritance paradigms in several …

The hermaphroditic nematode Caenorhabditis elegans has been one of the primary model
systems in biology since the 1970s, but only within the last two decades has this nematode …

Microbes that protect their hosts from pathogens are widespread in nature and are attractive
disease control agents. Given that pathogen adaptation to barriers against infection can …

Caenorhabditis nematodes form an excellent model for studying how the mode of
reproduction affects genetic diversity, as some species reproduce via outcrossing whereas …

Using a new experimentally evolved multiparent mapping resource for C. elegans, Noble et
al. have outlined the genetic architecture of worm fertility.. Understanding the genetic basis …

There have been a variety of approaches taken to try to characterize and identify the genetic
basis of adaptation in nature, spanning theoretical models, experimental evolution studies …