Antecedents of major depressive, bipolar, and psychotic disorders: a systematic review and meta-analysis of prospective studies

R Uher, B Pavlova, S Najafi, N Adepalli, B Ross… - Neuroscience & …, 2024 - Elsevier
Major depressive, bipolar, or psychotic disorders are preceded by earlier manifestations in
behaviours and experiences. We present a synthesis of evidence on associations between …

Summarising Quantitative Outcomes in Parental Mental Illness Research

D Maybery, A Grant, G Piché, S Yates… - … Journal of Mental …, 2024 - Wiley Online Library
ABSTRACT A quarter of all children grow up in a family where a parent experiences a
mental illness (FaPMI). Research activity in this area is growing rapidly and it is now critical …

The Mood and Resilience in Offspring (MARIO) project: a longitudinal cohort study among offspring of parents with and without a mood disorder

A Vreeker, M Horsfall, M Eikelenboom, A Beerthuizen… - BMC psychiatry, 2024 - Springer
Background One of the most robust risk factors for developing a mood disorder is having a
parent with a mood disorder. Unfortunately, mechanisms explaining the transmission of …

Intergenerational transmission of psychopathology across three generations: the role of social support

Y Xerxa, MHJ Hillegers, E Mesman, H Tiemeier… - European Child & …, 2024 - Springer
Psychopathology runs in families and affects functioning of individuals and their family
members. This study assessed the intergenerational transmission of psychopathology risk …

Integrating polygenic scores and phenotypic data to understand psychiatric outcomes

K Scott, M Alda - American Journal of Psychiatry, 2024 - psychiatryonline.org
Genetic predisposition plays an important role in the development and clinical management
of most psychiatric conditions. Traditionally, it is evaluated through family history, but recent …

Do Polygenic Scores Inform Psychiatric Disease Risk After Considering Family History?

JM Biernacka - American Journal of Psychiatry, 2023 - Am Psychiatric Assoc
Psychiatric disorders are heritable, and thus both family history and an individual's genetic
makeup are related to their risk of illness. It has long been known that family history can help …

[HTML][HTML] Genetic Correlates of Treatment-Resistant Depression: Insights from Polygenic Scores Across Cognitive, Temperamental, and Sleep Traits in the All of US …

B Xu, KL Forthman, R Kuplicki, J Ahern, R Loughnan… - medRxiv, 2024 - ncbi.nlm.nih.gov
Background Treatment-resistant depression (TRD) is a major challenge in mental health,
affecting a significant number of patients and leading to considerable economic and social …

Enhancement of Indonesia's blue economy sector through innovation and competitive advantage based on Resource-Based View theory

A Rianawati, NK Darmasetiawan… - … and Perspectives in …, 2024 - repository.ubaya.ac.id
Indonesia's blue economy holds immense potential due to the marine ecosystem and
maritime area, encompassing the marine fisheries sector, marine tourism, and fisheries …

Insights From Genetic, Neuroimaging, and Behavioral Neuroscience Studies

NH Kalin - American Journal of Psychiatry, 2023 - Am Psychiatric Assoc
This issue of the Journal presents an interesting combination of genetic and neuroimaging
studies as well as a preclinical behavioral neuroscience study with translational …

Polygenic scores for psychiatric traits mediate the impact of multigenerational history for depression on offspring psychopathology

J Cha, E Lee, M van Dijk, B Kim, G Kim, E Murphy… - 2024 - researchsquare.com
A family history of depression is a well-documented risk factor for offspring psychopathology.
However, the genetic mechanisms underlying the intergenerational transmission of …