Cancer stem cells (CSCs) or tumor initiating cells (TICs) contribute to tumorigenesis,
metastasis, recurrence and chemoresistance. CD133, a pentaspan membrane glycoprotein …

The cancer stem cell (CSC) hypothesis, despite the limitations of the currently available
models and assays, has ushered in a new era of excitement in cancer research. The …

Evidence is accumulating that solid tumors contain a rare phenotypically distinct population
of cells, termed cancer stem cells (CSC), which give rise to and maintain the bulk of the …

Ovarian adenocarcinoma is characterized by a late detection, dissemination of cancer cells
into the whole peritoneum, and the frequent acquisition of chemoresistance. If these …

Epigenetic reprogramming plays a pivotal role during embryogenesis, including both
covalent and non-covalent modifications to chromatin. In this study, we investigated the role …

The cancer stem cell (CSC) model proposes that tumor development and progression are
fueled and sustained by undifferentiated cancer cells, endowed with self-renewal and tumor …

The concept of cancer stem cells (CSCs) proposes that solely CSCs are capable of
generating tumor metastases. However, how CSCs maintain their invasion and migration …

Inflammatory cytokines, components of cancer stem cells (CSCs) niche, could affect the
characteristics of CSCs such as self-renewal and metastasis. Interleukin-17 (IL-17) is a new …

Cancer stem cells are rare chemotherapy resistant cells within a tumor which can serve to
populate the bulk of a tumor with more differentiated daughter cells and potentially …

Tumor angiogenesis and cancer stem cells (CSCs) are two major hallmarks of solid tumors.
They have long received attention for their critical roles in tumor progression, metastasis and …