Applications of the method of continuous variations (MCV or the Method of Job) to problems
of interest to organometallic chemists are described. MCV provides qualitative and …

Organolithium reagents were first prepared in 1917 by Schlenk 1a and developed in the
following three decades by major contributions from Ziegler (who first prepared n-BuLi and …

Organic superbases are a distinct and increasingly utilized class of Brønsted base that
possess properties complementary to common inorganic bases. This Concept article …

Nuclear magnetic resonance (NMR) is the most powerful and widely utilized technique for
determining molecular structure. Although traditional NMR data analysis involves the …

Most synthetic chemists will have at some point utilized a sterically demanding secondary
amide (R2N−). The three most important examples, lithium 1, 1, 1, 3, 3, 3 …

Organolithium chemistry! An overview of the structure formation principles and the strong
structure–reactivity relationship of lithium organics is given. By means of the commonly used …

Detailed mechanistic studies on the palladium-catalyzed direct arylation of pyridine N-
oxides are presented. The order of each reaction component is determined to provide a …

Organometallic chemistry is one of the key assets to successfully achieve complex organic
transformations. Numerous tools have been conceived and developed to address problems …

Mixing two organometallic reagents leads to synergic mixed aggregates or ate complexes
for which we suggest (as well as for oligomers) the name “Mixed AggregAte” or MAA. The …

A highly practical and general palladium-catalyzed methodology for the α, β-
dehydrogenation of esters and nitriles is reported. Generation of a zinc enolate or …