Perivascular spaces in the brain: anatomy, physiology and pathology
JM Wardlaw, H Benveniste, M Nedergaard… - Nature Reviews …, 2020 - nature.com
Perivascular spaces include a variety of passageways around arterioles, capillaries and
venules in the brain, along which a range of substances can move. Although perivascular …
venules in the brain, along which a range of substances can move. Although perivascular …
Understanding the role of the perivascular space in cerebral small vessel disease
R Brown, H Benveniste, SE Black… - Cardiovascular …, 2018 - academic.oup.com
Small vessel diseases (SVDs) are a group of disorders that result from pathological
alteration of the small blood vessels in the brain, including the small arteries, capillaries and …
alteration of the small blood vessels in the brain, including the small arteries, capillaries and …
[HTML][HTML] Perivascular spaces and brain waste clearance systems: relevance for neurodegenerative and cerebrovascular pathology
K Gouveia-Freitas, AJ Bastos-Leite - Neuroradiology, 2021 - Springer
Perivascular spaces (PVS) of the brain, often called Virchow-Robin spaces, comprise fluid,
cells and connective tissue, and are externally limited by astrocytic endfeet. PVS are …
cells and connective tissue, and are externally limited by astrocytic endfeet. PVS are …
Perivascular spaces and their associations with risk factors, clinical disorders and neuroimaging features: a systematic review and meta-analysis
F Francis, L Ballerini… - International Journal of …, 2019 - journals.sagepub.com
Background Perivascular spaces, visible on brain magnetic resonance imaging, are thought
to be associated with small vessel disease, neuroinflammation, and to be important for …
to be associated with small vessel disease, neuroinflammation, and to be important for …
[HTML][HTML] Imaging perivascular space structure and function using brain MRI
In this article, we provide an overview of current neuroimaging methods for studying
perivascular spaces (PVS) in humans using brain MRI. In recent years, an increasing …
perivascular spaces (PVS) in humans using brain MRI. In recent years, an increasing …
[HTML][HTML] Perivascular unit: This must be the place. The anatomical crossroad between the immune, vascular and nervous system
F Troili, V Cipollini, M Moci, E Morena… - Frontiers in …, 2020 - frontiersin.org
Most neurological disorders seemingly have heterogenous pathogenesis, with overlapping
contribution of neuronal, immune and vascular mechanisms of brain injury. The perivascular …
contribution of neuronal, immune and vascular mechanisms of brain injury. The perivascular …
Physiology and clinical relevance of enlarged perivascular spaces in the aging brain
Perivascular spaces (PVS) are fluid-filled compartments that are part of the cerebral blood
vessel wall and represent the conduit for fluid transport in and out of the brain. PVS are …
vessel wall and represent the conduit for fluid transport in and out of the brain. PVS are …
Body mass index, time of day and genetics affect perivascular spaces in the white matter
The analysis of cerebral perivascular spaces (PVS) using magnetic resonance imaging
(MRI) allows to explore in vivo their contributions to neurological disorders. To date the …
(MRI) allows to explore in vivo their contributions to neurological disorders. To date the …
Association of MRI indices of glymphatic system with amyloid deposition and cognition in mild cognitive impairment and Alzheimer disease
K Kamagata, C Andica, K Takabayashi, Y Saito… - Neurology, 2022 - AAN Enterprises
Background and Objectives The glymphatic system is a whole-brain perivascular network,
which promotes CSF/interstitial fluid exchange. Alterations to this system may play a pivotal …
which promotes CSF/interstitial fluid exchange. Alterations to this system may play a pivotal …
[HTML][HTML] Image processing approaches to enhance perivascular space visibility and quantification using MRI
Imaging the perivascular spaces (PVS), also known as Virchow-Robin space, has significant
clinical value, but there remains a need for neuroimaging techniques to improve mapping …
clinical value, but there remains a need for neuroimaging techniques to improve mapping …