2018 ESC/ESH Guidelines for the management of arterial hypertension: The Task Force for the management of arterial hypertension of the European Society of …

B Williams, G Mancia, W Spiering… - European heart …, 2018 - academic.oup.com
Aims The expression of GADD153 (growth arrest and DNA damage-inducible gene 153), an
apoptosis-regulated gene, increases during endoplasmic reticulum (ER) stress. How …

Carotid body chemoreceptors: physiology, pathology, and implications for health and disease

R Iturriaga, J Alcayaga, MW Chapleau… - Physiological …, 2021 - journals.physiology.org
The carotid body (CB) is the main peripheral chemoreceptor for arterial respiratory gases O2
and CO2 and pH, eliciting reflex ventilatory, cardiovascular, and humoral responses to …

[PDF][PDF] Guía ESC/ESH 2018 sobre el diagnóstico y tratamiento de la hipertensión arterial

B Williams, G Mancia, W Spiering, E Agabiti Rosei… - Rev Esp …, 2019 - peroxfarma.com
La tarea de elaboración de GPC incluye la creación de herramientas educativas y
programas de implementación de las recomendaciones. Para su implementación, se …

[HTML][HTML] Regulation of breathing and autonomic outflows by chemoreceptors

PG Guyenet - Comprehensive Physiology, 2014 - ncbi.nlm.nih.gov
Lung ventilation fluctuates widely with behavior but arterial PCO 2 remains stable. Under
normal conditions, the chemoreflexes contribute to PaCO 2 stability by producing small …

2018 ESC/ESH Guidelines for the Management of Arterial Hypertension: The Task Force for the management of arterial hypertension of the European Society of …

B Williams, G Mancia, W Spiering… - … of Hypertension of …, 2019 - taylorfrancis.com
Guidelines summarize and evaluate available evidence with the aim of assisting health
professionals in selecting the best management strategies for an individual patient with a …

The nucleus of the solitary tract and the coordination of respiratory and sympathetic activities

DB Zoccal, WI Furuya, M Bassi, DSA Colombari… - Frontiers in …, 2014 - frontiersin.org
It is well known that breathing introduces rhythmical oscillations in the heart rate and arterial
pressure levels. Sympathetic oscillations coupled to the respiratory activity have been …

Neural regulation of cardiovascular response to exercise: role of central command and peripheral afferents

ACL Nobrega, DO′ Leary, BM Silva… - BioMed research …, 2014 - Wiley Online Library
During dynamic exercise, mechanisms controlling the cardiovascular apparatus operate to
provide adequate oxygen to fulfill metabolic demand of exercising muscles and to guarantee …

Purinergic receptors in the carotid body as a new drug target for controlling hypertension

W Pijacka, DJA Moraes, LEK Ratcliffe… - Nature medicine, 2016 - nature.com
In view of the high proportion of individuals with resistance to antihypertensive medication
and/or poor compliance or tolerance of this medication, new drugs to treat hypertension are …

Neuronal networks in hypertension: recent advances

PG Guyenet, RL Stornetta, GMPR Souza… - …, 2020 - Am Heart Assoc
Neurogenic hypertension is associated with excessive sympathetic nerve activity to the
kidneys and portions of the cardiovascular system. Here we examine the brain regions that …

Unilateral carotid body resection in resistant hypertension: a safety and feasibility trial

K Narkiewicz, LEK Ratcliffe, EC Hart, LJB Briant… - JACC: Basic to …, 2016 - jacc.org
Animal and human data indicate pathological afferent signaling emanating from the carotid
body that drives sympathetically mediated elevations in blood pressure in conditions of …