Light and optical techniques have made profound impacts on modern medicine, with
numerous lasers and optical devices currently being used in clinical practice to assess …

New technologies for imaging molecules, particularly optical technologies, are increasingly
being used to understand the complexity, diversity and in vivo behaviour of cancers.'Omic' …

Bacteria preferentially accumulating in tumor microenvironments can be utilized as natural
vehicles for tumor targeting. However, neither current chemical nor genetic approaches …

Blockade of the protein–protein interaction between the transmembrane protein
programmed cell death protein 1 (PD‐1) and its ligand PD‐L1 has emerged as a promising …

The success of fluorescence experiments requires attention to experimental details and an
understanding of the instrumentation. There are also many potential artifacts that can distort …

Molecular imaging can allow the non-invasive assessment of biological and biochemical
processes in living subjects. Such technologies therefore have the potential to enhance our …

Optical imaging of live animals has grown into an important tool in biomedical research as
advances in photonic technology and reporter strategies have led to widespread exploration …

Cancer nanotechnology is an interdisciplinary area of research in science, engineering, and
medicine with broad applications for molecular imaging, molecular diagnosis, and targeted …

Visibly fluorescent proteins (FPs) from jellyfish and corals have revolutionized many areas of
molecular and cell biology, but the use of FPs in intact animals, such as mice, has been …

There is a wealth of new fluorescent reporter technologies for tagging of many cellular and
subcellular processes in vivo. This imposed contrast is now captured with an increasing …