Restless legs syndrome
M Manconi, D Garcia-Borreguero… - Nature reviews Disease …, 2021 - nature.com
Restless legs syndrome (RLS) is a common sensorimotor disorder characterized by an urge
to move that appears during rest or is exacerbated by rest, that occurs in the evening or night …
to move that appears during rest or is exacerbated by rest, that occurs in the evening or night …
The comorbidity of insomnia, chronic pain, and depression: dopamine as a putative mechanism
Epidemiological, cross-sectional, and prospective studies suggest that insomnia, chronic
pain, and depression frequently co-occur and are mutually interacting conditions. However …
pain, and depression frequently co-occur and are mutually interacting conditions. However …
Altered brain iron homeostasis and dopaminergic function in restless legs syndrome (Willis–Ekbom disease)
CJ Earley, J Connor, D Garcia-Borreguero, P Jenner… - Sleep medicine, 2014 - Elsevier
Restless legs syndrome (RLS), also known as Willis–Ekbom Disease (WED), is a
sensorimotor disorder for which the exact pathophysiology remains unclear. Brain iron …
sensorimotor disorder for which the exact pathophysiology remains unclear. Brain iron …
The restless legs syndrome
C Trenkwalder, W Paulus, AS Walters - The lancet neurology, 2005 - thelancet.com
The restless legs syndrome is a common disorder that encompasses an idiopathic form of
genetic or unknown origin and symptomatic forms associated with many causes …
genetic or unknown origin and symptomatic forms associated with many causes …
Restless legs syndrome: pathophysiology, clinical presentation and management
C Trenkwalder, W Paulus - Nature Reviews Neurology, 2010 - nature.com
Restless legs syndrome (RLS) is a somatosensory network disorder that is clinically
diagnosed according to four main criteria: an urge to move the legs, usually associated with …
diagnosed according to four main criteria: an urge to move the legs, usually associated with …
New insights into the neurobiology of restless legs syndrome
Restless legs syndrome (RLS) is a common sensorimotor disorder, whose basic
components include a sensory experience, akathisia, and a sleep-related motor sign …
components include a sensory experience, akathisia, and a sleep-related motor sign …
The treatment of sleep disorders in Parkinson's disease: from research to clinical practice
G Loddo, G Calandra-Buonaura, L Sambati… - Frontiers in …, 2017 - frontiersin.org
Sleep disorders (SDs) are one of the most frequent non-motor symptoms of Parkinson's
disease (PD), usually increasing in frequency over the course of the disease and disability …
disease (PD), usually increasing in frequency over the course of the disease and disability …
International Continence Society consensus on the diagnosis and treatment of nocturia
Introduction Patients with nocturia have to face many hurdles before being diagnosed and
treated properly. The aim of this paper is to: summarize the nocturia patient pathway, explore …
treated properly. The aim of this paper is to: summarize the nocturia patient pathway, explore …
Animal models of sleep disorders
LA Toth, P Bhargava - Comparative medicine, 2013 - ingentaconnect.com
Problems with sleep affect a large part of the general population, with more than half of all
people in the United States reporting difficulties with sleep or insufficient sleep at various …
people in the United States reporting difficulties with sleep or insufficient sleep at various …
Brain-iron deficiency models of restless legs syndrome
Restless legs syndrome (RLS) is a common sensorimotor disorder for which two main
pathological elements are fairly well accepted: Brain iron deficiency (BID) and an altered …
pathological elements are fairly well accepted: Brain iron deficiency (BID) and an altered …